Evidence map›Paper›PMID 39017615›Full record

ArticleJournal of opioid management

Post-operative pain control in patients on buprenorphine or methadone for opioid use disorder.

Aurora Quaye, Tal Tsafnat, Janelle M Richard, Henry Stoddard, David J Gagnon

Abstract read
In one paragraph

Article in Journal of opioid management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aurora QuayeDepartment of Anesthesiology and Perioperative Medicine, Maine Medical Center, Portland; Division of Anesthesiology, Spectrum Healthcare Partners, South Portland, Maine; Tufts University School of Medicine, Boston, Massachusetts. ORCID: https://orcid.org/0000-0002-7573-2164.
Tal TsafnatUniversity of New England College of Osteopathic Medicine, Portland, Maine.
Janelle M RichardDepartment of Anesthesiology and Perioperative Medicine, Maine Medical Center, Portland, Maine. ORCID: https://orcid.org/0000-0002-2825-6134.
Henry StoddardCenter for Interdisciplinary Population & Health Research, Maine Health Institute for Research, Scarborough, Maine.
David J GagnonTufts University School of Medicine, Boston, Massachusetts; Department of Pharmacy, Maine Medical Center, Portland; MaineHealth Institute for Research, Scarborough, Maine.

Funding

Understanding Factors Influencing COVID-19 Testing and Vaccination in Immigrant Low-income and Homeless Populations and Testing Targeted InterventionsU54GM115516 · NIGMS · MAINEHEALTH · PI Frances E. Carr · 2017 to 2026
$51.6M
Telemedicine to Reduce Disparities in the Identification and Treatment of Neonatal EncephalopathyP20GM139745 · NIGMS · MAINEHEALTH · PI David B. Seder · 2021 to 2026
$19.2M
NIGMS NIH HHS P20 GM139745NIGMS NIH HHS U54 GM115516
6 · The paper itself

Abstract

objectiveThis study aimed to determine whether there is a difference in pain scores and opioid consumption after elective surgery in patients maintained on methadone or buprenorphine for opioid use disorder (OUD). Additionally, we investigated the impact of continuing or discontinuing methadone or buprenorphine on post-operative pain outcomes.

designA single-center retrospective cohort study.

settingTertiary care medical center. PATIENTS AND

participantsAdults aged 18 years or older with OUD maintained on buprenorphine or methadone who underwent elective surgery between January 1, 2017, and January 1, 2021.

interventionsPatients were identified through electronic medical records, and demographic and clinical data were collected.

main outcome measuresThe primary outcome was opioid consumption at 24 hours post-operatively, measured in milligram morphine equivalents. The secondary outcome was opioid consumption and pain scores up to 72 hours post-operatively, assessed using a numeric rating scale.

resultsThis study included 366 patients (64 percent on buprenorphine and 36 percent on methadone). Opioid utilization significantly increased when buprenorphine was not administered post-operatively. Both groups exhibited comparable total opioid consumption during the post-operative period. In the buprenorphine cohort, pain scores differed significantly based on the receipt of medications for OUD post-operatively.

conclusionsThis study reinforces existing evidence supporting the continuation of medications for opioid use disorder, specifically buprenorphine and methadone, during the perioperative period. Dissemination of guideline recommendations is essential to ensure optimal post-operative pain management for this patient population.

Indexed as

Analgesics, OpioidBuprenorphineMethadoneOpiate Substitution TreatmentOpioid-Related DisordersPostoperative PainAdultAgedElective Surgical ProceduresFemaleHumansMaleMiddle AgedPain ManagementPain MeasurementRetrospective StudiesAnalgesics, OpioidBuprenorphineMethadone

Identifiers

PMID39017615
PMCPMC11638846

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.