Evidence map›Paper›PMID 39016600›Full record

ArticleEnvironmental health perspectives2024

Midlife Residential Greenness and Late-Life Cognitive Decline among Nurses' Health Study Participants.

Marcia Pescador Jimenez, Maude Wagner, Francine Laden, Jaime E Hart, Francine Grodstein, Peter James

Abstract read
In one paragraph

Article in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The association between PMEnvironmental research · 2026
    Article
  5. Urban greenspace and dementia: Measures, mechanisms, and methodological guidance.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marcia Pescador JimenezDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA.ORCID 0000-0001-5240-7898
Maude WagnerDepartment of Internal Medicine, Rush Medical College and Rush Alzheimer's Disease Center, Chicago, Illinois, USA.
Francine LadenDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Jaime E HartDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Francine GrodsteinDepartment of Internal Medicine, Rush Medical College and Rush Alzheimer's Disease Center, Chicago, Illinois, USA.
Peter JamesDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Funding

Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
Built Environment Assessment through Computer visiON (BEACON): Applying Deep Learning to Street-Level and Satellite Images to Estimate Built Environment Effects on Cardiovascular HealthR01HL150119 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JAMES, PETER · 2020 to 2024
$3.9M
Neurodegenerative diseases and the role of green space: A deep learning assessmentR00AG066949 · NIA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI PESCADOR JIMENEZ, MARCIA IXCHEL · 2022 to 2024
$738k
NCI NIH HHS UM1 CA186107NHLBI NIH HHS R01 HL150119NIA NIH HHS R00 AG066949
6 · The paper itself

Abstract

backgroundMidlife residential exposure to greenspace may slow cognitive decline by increasing opportunities for physical activity and social connection, restoring attention, or reducing stress or adverse environmental exposures. However, prospective studies on the association between greenness and cognitive decline are sparse.

objectiveWe investigated the prospective association between greenness at midlife and cognitive decline later in life. We explored effect measure modification by apolipoprotein E (APOE)-ɛ4 carrier status, neighborhood socioeconomic status (NSES), and rural/urban regions.

methodsThe Nurses' Health Study (

resultsIn adjusted models, higher midlife greenness exposure [per interquartile range (IQR): 0.18] was associated with a 0.004-unit (95% CI: 0.001, 0.006) slower annual rate of cognitive decline. For comparison, we found that 1 year of age is related to a DISCUSSION: Higher midlife greenness exposure is associated with slower cognitive decline later in life. Future research is necessary to confirm these findings. https://doi.org/10.1289/EHP13588.

Indexed as

Cognitive DysfunctionAdultAgedEnvironmental ExposureFemaleHumansMiddle AgedNeighborhood CharacteristicsNursesProspective StudiesResidence CharacteristicsUnited States

Identifiers

PMID39016600
PMCPMC11253812

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.