Evidence map›Paper›PMID 39016553›Full record

ArticleInfection and immunity2024

Immunization with an mRNA DTP vaccine protects against pertussis in rats.

Graham J Bitzer, Nicholas A Fitzgerald, Megan A DeJong, Casey Cunningham, Joshua A Chapman, Dylan T Boehm, Gage M Pyles, Annalisa B Huckaby, Sarah J Miller, Spencer R Dublin and 3 more

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Graham J BitzerDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-9734-6424
Nicholas A FitzgeraldDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Megan A DeJongDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Casey CunninghamDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Joshua A ChapmanDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Dylan T BoehmDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Gage M PylesDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Annalisa B HuckabyDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Sarah J MillerDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Spencer R DublinDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Matthew D WardenDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.
Mariette BarbierDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-3250-3636
F Heath DamronDepartment of Microbiology, Immunology, and Cell Biology, West Virginia University , Morgantown, West Virginia, USA.ORCID 0000-0002-3140-402X

Funding

Development of mRNA-platform vaccinesR01AI153250 · NIAID · WEST VIRGINIA UNIVERSITY · PI DAMRON, FREDRICK HEATH · 2021 to 2025
$4.1M
Development of mucosal vaccines to protect against pertussisR01AI137155 · NIAID · WEST VIRGINIA UNIVERSITY · PI DAMRON, FREDRICK HEATH · 2019 to 2023
$2.9M
Vaccine Development Against Bacterial Pathogens Based on iron Acquisition ProteinsR01AI141671 · NIAID · WEST VIRGINIA UNIVERSITY · PI BARBIER, MARIETTE · 2019 to 2023
$2.5M
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 5RO1AI153250-03NIAID NIH HHS R01 AI137155NIAID NIH HHS R01 AI141671NIAID NIH HHS R01 AI153250
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bordetella pertussisRats, Sprague-DawleyWhooping CoughAnimalsAntibodies, BacterialDiphtheria-Tetanus-Pertussis VaccineFemaleImmunizationImmunoglobulin GmRNA VaccinesRatsAntibodies, BacterialDiphtheria-Tetanus-Pertussis VaccineImmunoglobulin GmRNA Vaccinesaerosol bacterial challengeBordetella pertussiscoughingleukocytosispertussispertussis rat modelwhooping cough

Identifiers

PMID39016553
PMCPMC11320933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.