Evidence map›Paper›PMID 39016365›Full record

ArticleBrazilian oral research2024

Dentin erosive wear is reduced by fluoride varnishes containing nanosized sodium trimetaphosphate in vitro.

Isabela Ferreira da Silva, Letícia Cabrera Capalbo, Renan Dal-Fabbro, Mayra Frasson Paiva, Thayse Yumi Hosida, Liliana Carolina Báez-Quintero, Caio Sampaio, Douglas Roberto Monteiro, Alberto Carlos Botazzo Delbem, Juliano Pelim Pessan

Abstract readEvaluation Study
In one paragraph

Article in Brazilian oral research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Frontiers in dental medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabela Ferreira da SilvaUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0009-0009-5760-1337
Letícia Cabrera CapalboUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0003-2775-9263
Renan Dal-FabbroUniversity of Michigan, School of Dentistry, Department of Cariology, Restorative Sciences, and Endodontics, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-4125-8441
Mayra Frasson PaivaUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0002-4677-1420
Thayse Yumi HosidaUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0001-7007-330X
Liliana Carolina Báez-QuinteroUniversidad Cooperativa de Colombia, Facultad de Odontologia, Bogotá, Colombia.ORCID http://orcid.org/0000-0002-1354-8433
Caio SampaioUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0002-6861-7205
Douglas Roberto MonteiroUniversidad Cooperativa de Colombia, Facultad de Odontologia, Bogotá, Colombia.ORCID http://orcid.org/0000-0001-5229-5259
Alberto Carlos Botazzo DelbemUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0002-8159-4853
Juliano Pelim PessanUniversidade Estadual Paulista - Unesp, School of Dentistry of Araçatuba, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0002-1550-3933

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the effect of fluoride varnishes containing micrometric or nanosized sodium trimetaphosphate (TMP) on dentin erosive wear in vitro. Bovine root dentin blocks were selected by surface hardness and randomly divided into five experimental groups/varnishes (n = 20/group): placebo, 5% sodium fluoride (NaF); 5% NaF+5% micrometric TMP; 5% NaF+2.5% nanosized TMP; and 5% NaF+5% nanosized TMP. Half of the surface of all blocks received a single application of the assigned varnish, with subsequent immersion in artificial saliva for 6 h. Varnishes were then removed and the blocks were immersed in citric acid (90 s, 4×/day, 5 days). After each erosive cycle, ten blocks of each group were immersed in a placebo dentifrice for 15 s (ERO), while the other ten blocks were subjected to abrasion by brushing (ERO+ABR). Dentin erosive wear was assessed by profilometry. Data were submitted to 2-way ANOVA and to the Holm-Sidak test (p<0.05). Dentin erosive wear was significantly higher for ERO+ABR than for ERO for all varnishes. TMP-containing varnishes promoted superior effects against dentin erosive wear compared with 5% NaF alone; and 5% nanosized TMP led to the lowest wear among all varnishes. In conclusion, the addition of TMP to conventional fluoride varnish (i.e., varnish containing only NaF) enhanced its protective effects against bovine root dentin erosion and erosion+abrasion. Additionally, the use of 5% nanosized TMP led to superior effects in comparison to 5% micrometric TMP, both for erosion and erosion+abrasion in vitro.

Indexed as

DentinFluorides, TopicalMaterials TestingPolyphosphatesSodium FluorideSurface PropertiesTooth ErosionAnalysis of VarianceAnimalsCattleCitric AcidHardness TestsNanoparticlesRandom AllocationReference ValuesReproducibility of ResultsCitric AcidFluorides, TopicalPolyphosphatesSaliva, ArtificialSodium Fluoridetrimetaphosphoric acid

Identifiers

PMID39016365
PMCPMC11376609

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.