Evidence map›Paper›PMID 39016060›Full record

ArticleNanomedicine (London, England)2024

Therapeutic effect of E-Lip-siRNA-sFlt1 on pre-eclampsia: targeted gene silencing and improved pregnancy outcomes.

Jinhua Dong, Yingying Zhang, Jingsheng Zhou, Shuhui Mao, Jianfen Tang, Suping Li, Qiang Ma, Ling Ai, Wei Wang, Guanghao Zhu and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanomedicine (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jinhua DongDepartment of Obstetrics & Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, China.
Yingying ZhangSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Jingsheng ZhouSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Shuhui MaoDepartment of Obstetrics & Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, China.
Jianfen TangThe Women & Children Hospital Affiliated to Jiaxing University, 2468 Middle Ring Eastern Road, Jiaxing City, Zhejiang, 314000, China.
Suping LiThe Women & Children Hospital Affiliated to Jiaxing University, 2468 Middle Ring Eastern Road, Jiaxing City, Zhejiang, 314000, China.
Qiang MaThe Women & Children Hospital Affiliated to Jiaxing University, 2468 Middle Ring Eastern Road, Jiaxing City, Zhejiang, 314000, China.
Ling AiThe Women & Children Hospital Affiliated to Jiaxing University, 2468 Middle Ring Eastern Road, Jiaxing City, Zhejiang, 314000, China.
Wei WangSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Guanghao ZhuSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Huijing ShaoSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Yingdi MengSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Huaiwen ChenSunlipo Biotech Research Center for Nanomedicine, Shanghai, 201507, People's Republic of China.
Danqing ChenDepartment of Obstetrics & Gynecology, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, 310006, China.

Funding

the Technology Bureau of Jiaxing, Zhejiang Province 2023AD31099Zhejiang Provincial National Science Foundation of China LBY22H180002
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene SilencingLiposomesPre-EclampsiaRNA, Small InterferingVascular Endothelial Growth Factor Receptor-1AnimalsDisease Models, AnimalErbB ReceptorsFemaleHumansPlacentaPregnancyPregnancy OutcomeRatsRats, Sprague-DawleyErbB ReceptorsFlt1 protein, ratLiposomesRNA, Small InterferingVascular Endothelial Growth Factor Receptor-1EGFRnanoliposomesplacental targetingpre-eclampsiasiRNA

Identifiers

PMID39016060
PMCPMC11389737

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.