Evidence map›Paper›PMID 39015862›Full record

ArticleCureus2024

The Distribution Patterns of Rhesus (Rh) Antigens.

Babita Raghuwanshi, Kanchan Ahuja, Garima Sharma, Kalpana Sharma, Meghna Singh, Aarti Yadav, Subhash Kumar, Pankaj K Sharma, Harish Chander, Devesh Dubey

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Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Babita RaghuwanshiTransfusion Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.
Kanchan AhujaBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Garima SharmaBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Kalpana SharmaBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Meghna SinghBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Aarti YadavBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Subhash KumarBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Pankaj K SharmaBlood Reagent Laboratory, National Institute of Biologicals, Noida, IND.
Harish ChanderBiotherapeutics Research Laboratory, National Institute of Biologicals, Noida, IND.
Devesh DubeyTransfusion Medicine, All India Institute of Medical Sciences, Bhopal, Bhopal, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe determination of one's blood group is dictated by the inheritance-based diversity in the presence or absence of RBC antigens on the surface. Extended Rhesus (Rh) antigens are the most clinically relevant antigens of blood group systems after the ABO blood group system in transfusion medicine. The aim of this study was to serologically assess the prevalence of extended Rh antigens across diverse blood group systems.

methodsA total of 2043 samples were tested for the ABO blood group and Rh typing with monoclonal antisera. The Rh phenotyping (C, c, E, e ) was performed on all the samples.

resultsThe most frequently observed ABO blood group was O (36.5%), while AB (13.6%) was identified as the least prevalent. Positive Rh D antigen was found in 91.6% of tested samples, while 8.4% were Rh D-negative. The most frequently encountered antigen was e, followed by D, while the least prevalent was E. DISCUSSION: Establishing a Rh phenotype repository for blood donors and conducting Rh phenotype assessments as part of pretransfusion testing before initiating the initial blood transfusion for each patient could significantly lower the patients' incidence of alloimmunization.

Indexed as

alloimmunizationd antigene antigenrh antigenstransfusion

Identifiers

PMID39015862
PMCPMC11251307

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