Evidence map›Paper›PMID 39015560›Full record

ArticleCurrent transplantation reports2023

Novel Imaging Technologies for Accurate Assessment of Cardiac Allograft Performance.

Manuela Lopera Higuita, Rohil Jain, Asishana A Osho, S Alireza Rabi, Timothy L Pruett, Richard N Pierson, Paul A Iaizzo, Shannon N Tessier

Abstract read
In one paragraph

Article in Current transplantation reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manuela Lopera HiguitaCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Rohil JainCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Asishana A OshoDivision of Cardiac Surgery, Corrigan Minehan Heart Center, Massachusetts General Hospital, MA, Boston, USA.
S Alireza RabiDivision of Cardiac Surgery, Corrigan Minehan Heart Center, Massachusetts General Hospital, MA, Boston, USA.
Timothy L PruettDivision of Solid Organ Transplantation and Department of Surgery, University of Minnesota, Minneapolis, MN, USA.
Richard N PiersonDepartment of Surgery and Center for Transplantation Sciences, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Paul A IaizzoVisible Heart Laboratories, Departments of Surgery and Biomedical EngineeringInstitute for Engineering in Medicine, University of Minnesota, MN 55455 Minneapolis, USA.
Shannon N TessierCenter for Engineering in Medicine and Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-2373-232X

Funding

Prolonging life-supported pig kidney and heart graft survival in baboons by suppressing inflammationU19AI090959 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MOHIUDDIN, MUHAMMAD M · 2010 to 2024
$26.3M
CRISPR-Modified Cardiac Xenograft TransplantationU01AI153612 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI PIERSON, RICHARD N · 2021 to 2024
$3.2M
High subzero heart preservation: from zebrafish to mammalsR01HL157803 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Shannon Noella Tessier · 2021 to 2026
$2.8M
A quantitative viability metric for liver transplantation using Resonance Raman SpectroscopyR01DK134590 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Shannon Noella Tessier · 2023 to 2026
$1.9M
Whole heart suspended animation: leveraging the zebrafish to solve the organ shortageR00HL143149 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI TESSIER, SHANNON NOELLA · 2021 to 2023
$747k
Whole heart suspended animation: leveraging the zebrafish to solve the organ shortageK99HL143149 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI TESSIER, SHANNON NOELLA · 2019 to 2020
$215k
NHLBI NIH HHS K99 HL143149NHLBI NIH HHS R00 HL143149NHLBI NIH HHS R01 HL157803NIAID NIH HHS U01 AI153612NIAID NIH HHS U19 AI090959NIDDK NIH HHS R01 DK134590
6 · The paper itself

Abstract

Purpose of the Review: The current lack of objective and quantitative assessment techniques to determine cardiac graft relative viability results in risk-averse decision-making, which negatively impact the utilization of cardiac grafts. The purpose of this review is to highlight the current deficiencies in cardiac allograft assessment before focusing on novel cardiac assessment techniques that exploit conventional and emerging imaging modalities, including ultrasound, magnetic resonance, and spectroscopy. Recent Findings: Extensive work is ongoing by the scientific community to identify improved objective metrics and tools for cardiac graft assessment, with the goal to safely increasing the number and proportion of hearts accepted for transplantation. Summary: This review briefly discusses the in situ and ex vivo tools currently available for clinical organ assessment, before focusing on the individual capabilities of ultrasound, magnetic resonance, and spectroscopy to provide insightful, non-invasive information regarding cardiac graft functional and metabolic status that may be used to predict outcome after transplantation.

Indexed as

Heart assessmentHeart transplantImaging techniquesMagnetic resonance imagingSpectroscopyUltrasound

Identifiers

PMID39015560
PMCPMC11251714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.