Evidence map›Paper›PMID 39015551›Full record

ArticleLaryngoscope investigative otolaryngology2024

Current otolaryngologic applications of the novel self-assembling RADA-16 peptide matrix.

Kaitlynne Y Pak, Dennis M Tang, Satyan B Sreenath, Christopher J Ito, Brent A Senior, Kent K Lam, Thomas S Higgins, Kevin Hur, Benjamin Tam, Ayesha N Khalid and 1 more

Abstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kaitlynne Y PakDivision of Otolaryngology-Head & Neck Surgery Cedars-Sinai Medical Center Los Angeles USA.ORCID https://orcid.org/0000-0001-7771-1802
Dennis M TangDivision of Otolaryngology-Head & Neck Surgery Cedars-Sinai Medical Center Los Angeles USA.
Satyan B SreenathDepartment of Otolaryngology-Head & Neck Surgery Indiana University Bloomington USA.
Christopher J ItoDepartment of Otolaryngology-Head & Neck Surgery University of Massachusetts Amherst USA.ORCID https://orcid.org/0000-0002-6782-1490
Brent A SeniorDepartment of Otolaryngology-Head & Neck Surgery University of North Carolina Chapel Hill USA.
Kent K LamDepartment of Otolaryngology-Head & Neck Surgery Eastern Virginia Medical School Norfolk UK.ORCID https://orcid.org/0000-0002-1835-5390
Thomas S HigginsDepartment of Otolaryngology-Head & Neck Surgery University of Louisville Louisville USA.ORCID https://orcid.org/0000-0002-2020-6386
Kevin HurDepartment of Otolaryngology-Head & Neck Surgery University of Southern California Los Angeles USA.
Benjamin TamDepartment of Otolaryngology-Head & Neck Surgery University of Southern California Los Angeles USA.ORCID https://orcid.org/0000-0001-7559-3849
Ayesha N KhalidDivision of Otolaryngology-Head & Neck Surgery Harvard Medical School and Cambridge Health Alliance Boston USA.
Arthur W WuDivision of Otolaryngology-Head & Neck Surgery Cedars-Sinai Medical Center Los Angeles USA.ORCID https://orcid.org/0000-0001-8993-6355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel bioresorbable agent on the market is PuraGel® (3-D Matrix, Tokyo, Japan), a RADA-16 product that acts as a synthetic hemostatic and space-filling gel that promotes wound healing and prevents adhesion formation. Given the reported benefits of accelerated wound healing and scar tissue prevention, there are multiple otolaryngologic applications where RADA-16 might improve outcomes. Our study highlights current utilization and associated post-operative complications with this product.

Indexed as

hemostasisnasal/sinus surgeryRADA‐16wound healing

Identifiers

PMID39015551
PMCPMC11250146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.