Evidence map›Paper›PMID 39015471›Full record

ArticleJTCVS open2024

Outcomes of single- versus multi-port video-assisted thoracoscopic surgery: Data from a multicenter randomized controlled trial of video-assisted thoracoscopic surgery versus thoracotomy for lung cancer.

Eric Lim, Rosie A Harris, Tim Batchelor, Gianluca Casali, Rakesh Krishnadas, Sofina Begum, Simon Jordan, Joel Dunning, Ian Paul, Michael Shackcloth and 14 more

Abstract read
In one paragraph

Article in JTCVS open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Initial outcomes with uniportal video-assisted lung resection.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Eric LimRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Rosie A HarrisBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Tim BatchelorSt Bartholomew's Hospital, London, United Kingdom.
Gianluca CasaliUniversity Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.
Rakesh KrishnadasUniversity Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom.
Sofina BegumRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Simon JordanRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Joel DunningThe James Cook University Hospital, Middlesbrough, United Kingdom.
Ian PaulThe James Cook University Hospital, Middlesbrough, United Kingdom.
Michael ShackclothLiverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Sarah FeeneyLiverpool Heart and Chest Hospital, Liverpool, United Kingdom.
Vladimir AnikinRoyal Brompton and Harefield Hospitals, Part of Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Niall McgonigleBelfast Trust Hospitals, Belfast, United Kingdom.
Hazem FallouhHeartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Luis HernandezHeartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.
Franscesco Di ChiaraOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Dionisios StavrouliasOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Mahmoud LoubaniCastle Hill Hospital, Hull, United Kingdom.
Syed QadriCastle Hill Hospital, Hull, United Kingdom.
Vipin ZamvarEdinburgh Royal Infirmary, Edinburgh, United Kingdom.
Lucy MarshallEdinburgh Royal Infirmary, Edinburgh, United Kingdom.
Surinder KaurBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Chris A RogersBristol Trials Centre, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
VIOLET Trialists

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Surgery through a single port may be less painful because access is supplied by 1 intercostal nerve or more painful because multiple instruments are used in 1 port. We analyzed data collected from the video-assisted thoracoscopic surgery group of a randomized controlled trial to compare differences in pain up to 1 year. Methods: Groups were compared in a prespecified exploratory analysis using direct (regression) and indirect comparison (difference with respect to thoracotomy). In-hospital visual analogue scale pain scores were used, and analgesic ratios were calculated. After discharge, pain was evaluated using European Organization for Research and Treatment of Cancer Quality of Life Questionnaires-Core 30 scores up to 1 year. Results: From July 2015 to February 2019, we randomized 503 participants. After excluding 50 participants who did not receive lobectomy, surgery was performed using a single port in 42 participants (predominately by a single surgeon), multiple ports in 166 participants, and thoracotomy in 245 participants. No differences were observed in-hospital between single- and multiple-port video-assisted thoracoscopic surgery when modeled using a direct comparison, mean difference of -0.24 (95% CI, -1.06 to 0.58) or indirect comparison, mean difference of -0.33 (-1.16 to 0.51). Mean analgesic ratio (single/multiple port) was 0.75 (0.64 to 0.87) for direct comparison and 0.90 (0.64 to 1.25) for indirect comparison. After discharge, pain for single-port video-assisted thoracoscopic surgery was lower than for multiple-port video-assisted thoracoscopic surgery (first 3 months), and corresponding physical function was higher up to 12 months. Conclusions: There were no consistent differences for in-hospital pain when lobectomy was undertaken using 1 or multiple ports. However, better pain scores and physical function were observed for single-port surgery after discharge.

Indexed as

multi-port VATSpostoperative painsingle-port VATS

Identifiers

PMID39015471
PMCPMC11247214

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.