Evidence map›Paper›PMID 39015302›Full record

ArticleEFSA journal. European Food Safety Authority2024

Guidance on risk-benefit assessment of foods.

EFSA Scientific Committee, Simon John More, Diane Benford, Susanne Hougaard Bennekou, Vasileios Bampidis, Claude Bragard, Thorhallur Ingi Halldorsson, Antonio F Hernández-Jerez, Kostas Koutsoumanis, Claude Lambré and 17 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Risk assessment of replacing synthetic preservatives with natural ingredients.EFSA journal. European Food Safety Authority · 2025
    Article
  9. RBA4SDS - Risk-benefit assessment for sustainable dietary shifts.EFSA journal. European Food Safety Authority · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

EFSA Scientific Committee
Simon John More
Diane Benford
Susanne Hougaard Bennekou
Vasileios Bampidis
Claude Bragard
Thorhallur Ingi Halldorsson
Antonio F Hernández-Jerez
Kostas Koutsoumanis
Claude Lambré
Kyriaki Machera
Ewen Mullins
Søren Saxmose Nielsen
Josef Schlatter
Dieter Schrenk
Dominique Turck
Androniki Naska
Morten Poulsen
Jukka Ranta
Salomon Sand
Heather Wallace
Maria Bastaki
Djien Liem
Anthony Smith
Ermolaos Ververis
Giorgia Zamariola
Maged Younes

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The EFSA Scientific Committee has updated its 2010 Guidance on risk-benefit assessment (RBA) of foods. The update addresses methodological developments and regulatory needs. While it retains the stepwise RBA approach, it provides additional methods for complex assessments, such as multiple chemical hazards and all relevant health effects impacting different population subgroups. The updated guidance includes approaches for systematic identification, prioritisation and selection of hazardous and beneficial food components. It also offers updates relevant to characterising adverse and beneficial effects, such as measures of effect size and dose-response modelling. The guidance expands options for characterising risks and benefits, incorporating variability, uncertainty, severity categorisation and ranking of different (beneficial or adverse) effects. The impact of different types of health effects is assessed qualitatively or quantitatively, depending on the problem formulation, scope of the RBA question and data availability. The integration of risks and benefits often involves value-based judgements and should ideally be performed with the risk-benefit manager. Metrics such as Disability-Adjusted Life Years (DALYs) and Quality-Adjusted Life Years (QALYs) can be used. Additional approaches are presented, such as probability of all relevant effects and/or effects of given severities and their integration using severity weight functions. The update includes practical guidance on reporting results, interpreting outcomes and communicating the outcome of an RBA, considering consumer perspectives and responses to advice.

Indexed as

benefit–riskfood safetyRBArisk–benefitrisk–benefit assessmentrisk–benefit communicationrisk ranking

Identifiers

PMID39015302
PMCPMC11250173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.