Evidence map›Paper›PMID 39015269›Full record

ArticleACS medicinal chemistry letters2024

Investigation of Isobactin Analogues of Teixobactin.

Chelsea R Jones, Grant H Lai, Maria Sophia Teresa Lee Padilla, James S Nowick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Bacterial cell envelope-targeting antibiotics.Nature reviews. Microbiology · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chelsea R JonesDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Grant H LaiDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID https://orcid.org/0000-0001-8620-3113
Maria Sophia Teresa Lee PadillaDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
James S NowickDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID https://orcid.org/0000-0002-2273-1029

Funding

Amyloidogenic AntibioticsR21AI156565 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI NOWICK, JAMES S · 2021 to 2022
$403k
NIAID NIH HHS R21 AI156565
6 · The paper itself

Abstract

Although teixobactin is a promising antibiotic drug candidate against Gram-positive bacteria, it aggregates to form gels that may limit intravenous administration. We previously reported

Identifiers

PMID39015269
PMCPMC11247654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.