Evidence map›Paper›PMID 39014961›Full record

ArticleACS chemical biology2024

Pseudouridine Detection and Quantification Using Bisulfite Incorporation Hindered Ligation.

Yutao Zhao, Xinyuan Ma, Chang Ye, Wenlong Li, Kinga Pajdzik, Qing Dai, Hui-Lung Sun, Chuan He

Abstract read
In one paragraph

Article in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Compendium of RNA modifications for bacterial stress adaptation.Microbiology and molecular biology reviews : MMBR · 2026
    Review
  2. Ribosome Molecular Aging Shapes Translation Dynamics.bioRxiv : the preprint server for biology · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Functions and therapeutic applications of pseudouridylation.Nature reviews. Molecular cell biology · 2025
    Review
  7. Review
  8. Article
  9. Advancements in pseudouridine modifying enzyme and cancer.Frontiers in cell and developmental biology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yutao ZhaoDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-4496-1394
Xinyuan MaDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Chang YeDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0003-0236-5671
Wenlong LiDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Kinga PajdzikDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Qing DaiDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Hui-Lung SunDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.
Chuan HeDepartment of Chemistry, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0003-4319-7424

Funding

Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Howard Hughes Medical InstituteNHGRI NIH HHS RM1 HG008935
6 · The paper itself

Abstract

Pseudouridine (Ψ) is a widespread RNA modification found in various RNA species, including rRNA, tRNA, snRNA, mRNA, and long noncoding RNA (lncRNA). Understanding the function of Ψ in these RNA types requires a robust method for the detection and quantification of the Ψ level at single-nucleotide resolution. A previously used method utilizes Ψ labeling by N-cyclohexyl-

Indexed as

PseudouridineSulfitesHumansRNA, Long NoncodingRNA, MessengerRNA, Ribosomalhydrogen sulfitePseudouridineRNA, Long NoncodingRNA, MessengerRNA, RibosomalSulfites

Identifiers

PMID39014961
PMCPMC12043245

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.