Regioconvergent Nucleophilic Substitutions with Morita-Baylis-Hillman Fluorides.

Jeffrey S S K Formen, Ciarán C Lynch, Eryn Nelson, Andi Yuan, Sarah E Steber, Christian Wolf

Abstract read

In one paragraph

Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Palladium-catalyzed asymmetric carbofluorination ofChemical communications (Cambridge, England) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey S S K FormenDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.

Ciarán C LynchDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.

Eryn NelsonDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.

Andi YuanDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.

Sarah E SteberDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.

Christian WolfDepartment of Chemistry, Georgetown University, 37th and O Streets, Washington, District of Columbia 20057, United States.ORCID 0000-0002-4447-3753

Funding

Synthesis of Chiral Organofluorines via Catalytic Asymmetric C-C Bond Formation wR15GM106260 · NIGMS · GEORGETOWN UNIVERSITY · PI Christian Wolf · 2013 to 2026

$2.2M

NIGMS NIH HHS R15 GM106260

6 · The paper itself

Abstract

Lithium iodide enables regioconvergent C-F bond functionalization of isomeric Morita-Baylis-Hillman fluorides with carbon, sulfur, and nitrogen nucleophiles. The defluorinative carbon-carbon and carbon-heteroatom bond formations give multifunctional compounds in excellent yields and with good to high diastereoselectivities at room temperature. The possibility of catalytic enantioselective allylation is also discussed.

Identifiers

PMID39014960

DOI10.1021/acs.joc.4c00660

PMCPMC11301663

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.