Evidence map›Paper›PMID 39014949›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2024

[Diagnostic efficacy of serum 14-3-3β protein combined with fractional exhaled nitric oxide and conventional ventilatory lung function parameters for bronchial asthma in children].

Shu-Fang Li, Guang-En Guo, Yue-Qin Yang, Xiao-Man Xiong, Shi-Wei Zheng, Xue-Li Xie, Yan-Li Zhang

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Shu-Fang LiDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Guang-En GuoDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Yue-Qin YangDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xiao-Man XiongDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Shi-Wei ZhengDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Xue-Li XieDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Yan-Li ZhangDepartment of Pediatrics, Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the diagnostic efficacy of serum 14-3-3β protein combined with fractional exhaled nitric oxide (FeNO) and conventional ventilatory lung function parameters in diagnosing bronchial asthma (referred to as "asthma") in children.

methodsA prospective study included 136 children initially diagnosed with asthma during an acute episode as the asthma group, and 85 healthy children undergoing routine health checks as the control group. The study compared the differences in serum 14-3-3β protein concentrations between the two groups, analyzed the correlation of serum 14-3-3β protein with clinical indices, and evaluated the diagnostic efficacy of combining 14-3-3β protein, FeNO, and conventional ventilatory lung function parameters for asthma in children.

resultsThe concentration of serum 14-3-3β protein was higher in the asthma group than in the control group (

conclusionsThe combination of serum 14-3-3β protein, FeNO, and the percentage of predicted value of forced expiratory flow at 75% of lung volume can significantly improve the diagnostic efficacy for asthma in children.

Indexed as

14-3-3 ProteinsAsthmaNitric OxideAdolescentBreath TestsChildChild, PreschoolFemaleFractional Exhaled Nitric Oxide TestingHumansMaleProspective StudiesRespiratory Function Tests14-3-3 ProteinsNitric Oxide14-3-3β proteinBronchial asthmaChildCombined diagnosisExhaled nitric oxideLung ventilatory function

Identifiers

PMID39014949
PMCPMC11562049

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.