Evidence map›Paper›PMID 39014878›Full record

ArticleExpert opinion on drug discovery2024

What impact does tautomerism have on drug discovery and development?

Devendra K Dhaked, Marc C Nicklaus

Abstract readEditorial
In one paragraph

Article in Expert opinion on drug discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Devendra K DhakedDepartment of Pharmacoinformatics, National Institute of Pharmaceutical Education and Research (NIPER), Kolkata, India.ORCID 0000-0001-6349-7649
Marc C NicklausComputer-Aided Drug Design Group, Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, NIH, Frederick, MD, USA.ORCID 0000-0002-4775-7030

Funding

HIV Integrase Modeling and Computer-Aided Inhibitor DevelopmentZIABC010524 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI NICKLAUS, MARC · 2009 to 2024
$2.6M
Better Understanding and Handling of TautomerismZIABC011785 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI NICKLAUS, MARC · 2017 to 2025
$2.0M
Intramural NIH HHS ZIA BC011785
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drug DevelopmentDrug DiscoveryDrug DesignHumansPharmaceutical PreparationsPharmaceutical PreparationsADMEBBBEpimerizationPreformulationTautomer

Identifiers

PMID39014878
PMCPMC11390299

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.