Evidence map›Paper›PMID 39014508›Full record

ArticleJournal of medical case reports2024

Whole-genome sequencing of multidrug-resistant Escherichia coli causing urinary tract infection in an immunocompromised patient: a case report.

Mohammed Yahya Ahmed, Babbiker Mohammed Taher Gorish, Esraa Mohammed Alhaj, Mayasir Abd Elmoniem Abd Elrhim, Shimaa Saifaldeen Siddig, Hisham N Altayb

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Mutation analysis of dihydrofolate reductase (Iranian journal of microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohammed Yahya AhmedDepartment of Microbiology, Faculty of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan. mohammedyhaya707@gmail.com.
Babbiker Mohammed Taher GorishDepartment of Microbiology, Faculty of Medical Laboratory Science, Omdurman Islamic University, Omdurman, Sudan.
Esraa Mohammed AlhajDepartment of Microbiology, Faculty of Medical Laboratory Science, Sudan University of Science and Technology, Khartoum, Sudan.
Mayasir Abd Elmoniem Abd ElrhimDepartment of Microbiology, Faculty of Medical Laboratory Science, Omdurman Islamic University, Omdurman, Sudan.
Shimaa Saifaldeen SiddigDepartment of Microbiology and Parasitology, Faculty of Medical Laboratory Science, Ibn Sina University, Khartoum, Sudan.
Hisham N AltaybDepartment of Biochemistry- Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEscherichia coli is a major human pathogen responsible for a broad range of clinical illnesses. It has been linked to endemic and epidemic nosocomial diseases caused by multidrug-resistant pathogens in Sudan as well as throughout the globe. CASE PRESENTATION: A 76-year-old African woman arrived at Saad Rashwan Medical Centre complaining of backaches and discomfort during urination. Throughout the preceding 5 years, the patient had recurrent urinary tract infections. Following overnight incubation at 37 °C, Escherichia coli was found in her midstream urine specimen on cysteine lactose electrolyte deficient agar media. Minimum inhibitory concentration (colorimetric/turbidimetric method) was employed to test a wide range of antimicrobial drugs against this bacterial strain, and the results revealed significant multidrug resistance. QIAamp

conclusionThis study found that the isolated Escherichia coli strain had varied antimicrobial resistance genes on the basis of whole-genome sequencing and phenotypic resistance analyses. Whole-genome sequencing is critical for control and preventative methods to battle the growing threat of antimicrobial resistance. A larger investigation is recommended for improved generalization of results.

Indexed as

Drug Resistance, Multiple, BacterialEscherichia coliEscherichia coli InfectionsImmunocompromised HostUrinary Tract InfectionsWhole Genome SequencingAgedAnti-Bacterial AgentsFemaleHumansMicrobial Sensitivity TestsPhylogenyAnti-Bacterial AgentsAntimicrobial resistanceEscherichia coliPhylogeny treeUrinary tract infectionsWhole-genome sequencing

Identifiers

PMID39014508
PMCPMC11253411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.