ArticleGeroScience2025
Revisiting the "Timed Up and Go" test: a 12-s cut-off can predict Hospitalization Associated Functional Decline in older adults.
Article in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
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- Evaluation of a Technology-Based Multifactorial Intervention for Improving Fall Risk: A Cluster-Randomized Controlled Trial.Research square · 2026Article
- Physical Activity, Cardiometabolic Health, and Functional Performance Across the Adult Lifespan: An Age-Stratified Real-World Primary Care Study.Sports (Basel, Switzerland) · 2026Article
- Sex Differences in Age-Related Functional Mobility Decline: A Moderated Mediation Analysis.Sports (Basel, Switzerland) · 2026Article
- Comparison of plantar pressure distribution, balance and functional parameters in older adults with high and low fall risk: a cross-sectional study.Irish journal of medical science · 2026Article
- Real-World Associations Between Physical Activity, LDL Cholesterol, and Functional Performance in Primary Care: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Validation of Falls Efficacy Scale Instrument in Romanian Adults with Type 2 Diabetes Mellitus: A Monocenter, Prospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- The impact of transitional care on geriatric rehabilitation outcomes: prevalence and associated factors of sarcopenia and malnutrition.Aging clinical and experimental research · 2026Observational
- Nonlinear Gait Variability and the Role of Cognitive-Physical Exercise in Mitigating Mobility Decline in Institutionalized Older Adults with Cognitive Impairment.Journal of functional morphology and kinesiology · 2026Article
- Oral health status and its relation to frailty in older adults: a cross-sectional study.BMC geriatrics · 2026Article
- Short-Term 8-Foot up and Go Responsiveness in Institutionalized vs. Community-Dwelling Older Adults.Sports (Basel, Switzerland) · 2026Article
- Effects of exercise regimens on balance ability in older patients with osteoporosis: a systematic review and Bayesian network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Review
- Efficacy of simultaneous aerobic and cognitive training (Activ4Brain) on physical fitness and body composition in older persons.Frontiers in aging · 2026Article
- Personalizing fall fear prevention in knee osteoarthritis: an interpretable prediction framework via IGKSO synchronous optimization and SHAP-based risk stratification.Frontiers in public health · 2026Article
- Gait and Dual-Task Performance in Older Adults with Suspected Cognitive Impairment: Effects of an 8-Week Exercise Program.Healthcare (Basel, Switzerland) · 2025Article
- Clinically Meaningful or Just Measurable? What Physiologic Outcomes Tell Us About Aging Interventions.Current geriatrics reports · 2025Article
- Differences in physical function across dementia subtypes and cognitive decline: a cross-sectional study.European journal of translational myology · 2025Article
- Assessment of the Concurrent Validity and Reliability of the Persian Version of the Pediatric Balance Scale in Schoolchildren with Down Syndrome.International journal of school health · 2025Article
- Association Between Physical Performance, Gait Variability, and Fall Risk in Community-Dwelling Older Adults: Predictive Validity of Step-Width Variability for Screening of Fall Risk.Life (Basel, Switzerland) · 2025Article
- Balance Abilities and Kinesiophobia in Women with Fibromyalgia Syndrome: A Cross-Sectional Comparative Study.Archives of rheumatology · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
Early detection of functional decline, a major risk among hospitalized older adults, can facilitate interventions that could significantly reduce it. We aimed to examine the contribution of the Timed Up and Go (TUG) test in predicting Hospitalization Associated Functional Decline (HAFD) among older adults, able to independently ambulate before admission. We used a cross-sectional study design; a total of 310 older adults (age ≥ 65) hospitalized in internal medicine wards between December 2018 and August 2020 were included; exclusion criteria were inability to ambulate, a diagnosis restricting mobility, hospitalization for end-of-life care, or impaired cognition. The Modified Barthel Index was used to assess HAFD; it was administered at admission to evaluate patients' independence in activities of daily living 2 weeks prior hospitalization, and at discharge. The TUG test was performed on admission and to predict significant functional decline (defined by a reduction of three points or more in the Modified Barthel Index), while accounting for demographics, length of hospitalization, comorbidity burden (Charlson's comorbidity index), and cognitive function (ALFI-MMSE). Participants were divided into three groups according to their TUG score-under or over a cut-off score of 12 s, or inability to complete the test. Adjusting for age, comorbidity, cognitive ability, and duration of hospitalization, the group that performed the test in less than 12 s showed no statistically significant change in the Modified Barthel Index, therefore no significant HAFD. The other groups showed a statistically significant decline in function. Risk for significant HAFD is currently underestimated in clinical settings, limited to subjective assessment, and underused in the context of implementing early interventions to prevent HAFD. The TUG may support screening for those at risk of hospitalizing-associated functional decline and could help identify patients suitable for preventative interventions.
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