Evidence map›Paper›PMID 39014076›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2024

The diagnostic accuracy of community spine radiology for adolescent idiopathic scoliosis brace candidates.

Dorothy J Kim, Jennifer A Dermott, Aya A Mitani, Andrea S Doria, Andrew W Howard, David E Lebel

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorothy J KimHospital for Sick Children, 555 University Avenue, Room S229, Toronto, ON M5G 1X8, Canada. dorothy.kim@sickkids.ca.ORCID http://orcid.org/0000-0003-4791-5489
Jennifer A DermottHospital for Sick Children, 555 University Avenue, Room S229, Toronto, ON M5G 1X8, Canada.ORCID http://orcid.org/0000-0001-9740-7197
Aya A MitaniDalla Lana School of Public Health, University of Toronto, Toronto, Canada.ORCID http://orcid.org/0000-0002-0373-5032
Andrea S DoriaHospital for Sick Children, 555 University Avenue, Room S229, Toronto, ON M5G 1X8, Canada.ORCID http://orcid.org/0000-0003-3202-0447
Andrew W HowardHospital for Sick Children, 555 University Avenue, Room S229, Toronto, ON M5G 1X8, Canada.
David E LebelHospital for Sick Children, 555 University Avenue, Room S229, Toronto, ON M5G 1X8, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe study aims to establish the diagnostic accuracy of community spine x-rays for brace candidates.

methodsA review of adolescent idiopathic scoliosis patients seen for initial visit at a tertiary care pediatric hospital was conducted (n = 170). The index test was the pre-referral community spine x-ray interpreted by a community radiologist. Measures of diagnostic accuracy for the index test were determined against the reference standard if images were obtained within 90 days (n = 111). The reference standard was the 3-foot standing EOS spine x-ray evaluated by spine specialists. Diagnostic criterion for a brace candidate was dichotomized by Cobb angle range (25-40°) according to Scoliosis Research Society criteria. Risser stage was not included given significant missing data in index reports. To mitigate the uncertainty around true progression, sensitivity analyses were conducted on a sub-sample of data when index test was within 60 days of the reference standard (n = 67).

resultsAccuracy of the community spine x-ray to detect a brace candidate was 65.8% (95% CI 56.2-74.5). Sensitivity of the index test was 65.4% with a false negative rate of 34.6%. Specificity was 66.1% with a false positive rate of 33.9%. Positive and negative predictive values were 63.0% and 68.4%, respectively. Of the total number of brace candidates (n = 52), 32.7% were missed because of underestimation in Cobb angle (95% CI 21.5-46.2). The proportion of missed brace candidates because of underestimation was unchanged with 60-day data (p = 0.37).

conclusionsInaccuracies in community spine radiology may lead to missed opportunities for non-operative treatment.

Indexed as

BracesRadiographyScoliosisAdolescentChildFemaleHumansMaleSensitivity and SpecificitySpineAccuracyCobb angleDiagnostic imagingIdiopathic scoliosisX-rays

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.