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ArticleSocial psychiatry and psychiatric epidemiology2025

Association between suicidal ideation, negative symptoms and theory of mind in first episode psychosis.

Mai Abdel Samie, Mohamed Nasreldin, Mostafa Shahin, Dalal A Amer, Rania Mamdouh Mohamed, Dina Badie Taher, Talha Sayed, Nadine Ahmed, Ali Mabrouk, Joseph Mamdouh and 1 more

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Article in Social psychiatry and psychiatric epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mai Abdel SamieDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.ORCID http://orcid.org/0000-0002-7987-3837
Mohamed NasreldinDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Mostafa ShahinDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Dalal A AmerDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Rania Mamdouh MohamedDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.ORCID http://orcid.org/0000-0002-4315-6270
Dina Badie TaherDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.ORCID http://orcid.org/0000-0002-9689-762X
Talha SayedDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Nadine AhmedDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Ali MabroukDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Joseph MamdouhDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt.
Sherif M GoharDepartment of Psychiatry, Faculty of Medicine, Cairo University, El Saraya Street, El Manyal, Cairo, 11956, Egypt. sherif.gohar@kasralainy.edu.eg.ORCID http://orcid.org/0000-0002-4420-5716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSuicidal thoughts are common among patients with first episode psychosis (FEP). The impact of symptoms' severity and social cognition on suicidal risk should be a focus of attention. This study aimed at assessment of the severity of suicidal ideation in patients with FEP and its potential association with the theory of mind (ToM) impairment and symptoms' severity.

methodsNinety-six participants were recruited consecutively and subdivided into three equal groups: FEP, schizophrenia, and healthy controls (HC). The symptoms' severity was assessed using Positive and Negative Syndrome Scale (PANSS) and Beck Depression Inventory (BDI). Suicidal ideation was evaluated using Beck Scale for Suicidal Ideation (BSSI). Reading the Mind in the Eyes revised version (RMET) was used to assess ToM.

resultsSuicidal ideation was significantly higher only in FEP compared to HC (p = 0.001). Both FEP and schizophrenia had substantially lower performance than HC on RMET (p < 0.001). Higher depression (β = 0.452, p = 0.007) and negative symptoms (β = 0.433, p = 0.027) appeared to be significantly associated with increased suicidal ideation severity in FEP while RMET did not.

conclusionPatients with FEP and chronic schizophrenia have comparable deficits in theory of mind dimension of social cognition. The severity of negative and depressive symptoms potentially contributes to the increased risk of suicide in FEP.

Indexed as

Psychotic DisordersSchizophreniaSchizophrenic PsychologySuicidal IdeationTheory of MindAdolescentAdultDepressionFemaleHumansMalePsychiatric Status Rating ScalesSeverity of Illness IndexYoung AdultDepressionMentalizationNegative symptomsSchizophreniaSocial cognitionSuicide

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.