ArticleScientific reports2024
Lung quantitative ultrasound to stage and monitor interstitial lung diseases.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Lung ultrasound in UIP and NSIP: clinical and functional associations.BMC pulmonary medicine · 2026Article
- Ultrasound structure function for quantitative assessment of steatotic liver disease based on total severity score.The Journal of the Acoustical Society of America · 2026Article
- Optimizing transducer choice for the detection of alveolar-interstitial syndrome in dogs and cats: an evidence-based review.Frontiers in veterinary science · 2026Review
- Random Forest-Based Detection of Metastases in Clinically Scanned Lymph Nodes Using Quantitative Ultrasound Imaging.Ultrasound in medicine & biology · 2025Article
- Imaging in animal models: bridging experimental findings and human pathophysiology.Critical care (London, England) · 2025Review
- Characterizing random complex biological media by quantifying ultrasound multiple scattering.Frontiers in acoustics · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
Chronic interstitial lung diseases (ILDs) require frequent point-of-care monitoring. X-ray-based methods lack resolution and are ionizing. Chest computerized tomographic (CT) scans are expensive and provide more radiation. Conventional ultrasound can detect severe lung damage via vertical artifacts (B-lines). However, this information is not quantitative, and the appearance of B-lines is operator- and system-dependent. Here we demonstrate novel ultrasound-based biomarkers to assess severity of ILDs. Lung alveoli scatter ultrasound waves, leading to a complex acoustic signature, which is affected by changes in alveolar density due to ILDs. We exploit ultrasound scattering in the lung and combine quantitative ultrasound (QUS) parameters, to develop ultrasound-based biomarkers that significantly correlate (p = 1e
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