Evidence map›Paper›PMID 39013943›Full record

ArticleScientific reports2024

Post-discharge spirometry evaluation in patients recovering from moderate-to-critical COVID-19: a cross-sectional study.

Chee-Shee Chai, Muhammad Amin Bin Ibrahim, Nur Amira Binti Azhar, Zulaika Binti Roslan, Rozila Binti Harun, Swarna Lata Krishnabahawan, Aruna A P Karthigayan, Roqiah Fatmawati Binti Abdul Kadir, Busra Binti Johari, Diana-Leh-Ching Ng and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Chee-Shee ChaiDepartment of Medicine, Faculty of Medicine and Health Science, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia. cschai@unimas.my.
Muhammad Amin Bin IbrahimDepartment of Internal Medicine, Faculty of Medicine, University Technology MARA, Sungai Buloh, Selangor, Malaysia.
Nur Amira Binti AzharClinical Research Centre, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Zulaika Binti RoslanClinical Research Centre, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Rozila Binti HarunClinical Research Centre, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Swarna Lata KrishnabahawanClinical Research Centre, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Aruna A P KarthigayanDepartment of Medicine, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Roqiah Fatmawati Binti Abdul KadirDepartment of Radiology, Faculty of Medicine, University Technology MARA, Sungai Buloh, Selangor, Malaysia.
Busra Binti JohariDepartment of Radiology, Faculty of Medicine, University Technology MARA, Sungai Buloh, Selangor, Malaysia.
Diana-Leh-Ching NgDepartment of Medicine, Faculty of Medicine and Health Science, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.
Benedict-Lim-Heng SimDepartment of Medicine, Sungai Buloh Hospital, Ministry of Health Malaysia, Sungai Buloh, Selangor, Malaysia.
Chong-Kin LiamDepartment of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Abdul Razak Bin MuttalifDepartment of Medicine, Faculty of Medicine, MAHSA University Malaysia, Jenjarom, Selangor, Malaysia.
Ahmad Hata Bin RasitDepartment of Orthopaedics, Faculty of Medicine and Health Science, University Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.
Kalaiarasu M PeariasamyInstitute for Clinical Research, National Institutes of Health, Ministry of Health Malaysia, Shah Alam, Selangor, Malaysia.
Mohammed Fauzi Bin Abdul RaniDepartment of Internal Medicine, Faculty of Medicine, University Technology MARA, Sungai Buloh, Selangor, Malaysia. mfar2718@gmail.com.

Funding

Aliran Pasifik (M) Sdn Bhd IRG/F05/APMSB/85317/2022Compass Medical Sdn Bhd GI/F05/CMSB/2021Lung Foundation of Malaysia GI/F05/LFM/2021Persatuan Pendidikan Kesihatan Paru-Paru IRG/F05/PPKP/85316/2022Selangor State Government 100 - 3/2/3JLD[25]Universiti Malaysia Sarawak F05/RISE/2089/2021
6 · The paper itself

Abstract

Understanding the prevalence of abnormal lung function and its associated factors among patients recovering from COVID-19 is crucial for enhancing post-COVID care strategies. This study primarily aimed to determine the prevalence and types of spirometry abnormalities among post-COVID-19 patients in Malaysia, with a secondary objective of identifying its associated factors. Conducted at the COVID-19 Research Clinic, Faculty of Medicine, University Technology MARA, from March 2021 to December 2022, this study included patients at least three months post-discharge from hospitals following moderate-to-critical COVID-19. Of 408 patients studied, abnormal spirometry was found in 46.8%, with 28.4% exhibiting a restrictive pattern, 17.4% showing preserved ratio impaired spirometry (PRISm), and 1.0% displaying an obstructive pattern. Factors independently associated with abnormal spirometry included consolidation on chest X-ray (OR 8.1, 95% CI 1.75-37.42, p = 0.008), underlying cardiovascular disease (OR 3.5, 95% CI 1.19-10.47, p = 0.023), ground-glass opacity on chest X-ray (OR 2.6, 95% CI 1.52-4.30, p < 0.001), and oxygen desaturation during the 6-min walk test (OR 1.9, 95% CI 1.20-3.06, p = 0.007). This study highlights that patients recovering from moderate-to-critical COVID-19 often exhibit abnormal spirometry, notably a restrictive pattern and PRISm. Routine spirometry screening for high-risk patients is recommended.

Indexed as

COVID-19Patient DischargeSpirometryAdultAgedCross-Sectional StudiesFemaleHumansLungMalaysiaMaleMiddle AgedPrevalenceSARS-CoV-2COVID-19ObstructivePRISmRadio-imagingRestrictiveSpirometry

Identifiers

PMID39013943
PMCPMC11252397

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.