ArticleNature communications2024
Phosphoribosylpyrophosphate synthetase as a metabolic valve advances Methylobacterium/Methylorubrum phyllosphere colonization and plant growth.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Keystone taxa of phyllosphere microbiome confer resistance to citrus bacterial canker in pomelo via multiple mechanisms.Journal of integrative plant biology · 2026Article
- Sources and traits of bacteria and fungi found in the near-surface atmosphere.Applied and environmental microbiology · 2026Article
- Antimicrobial and antioxidant activities of Methylobacterium phyllosphaerae KS50439 isolated from Antarctic seawater.Archives of microbiology · 2026Article
- Time-series dynamics and biocontrol potential of postharvest bacteria in litchi microbiota.Science China. Life sciences · 2026Article
- Engineering phosphoribosylpyrophosphate synthetase in Methylobacterium radiotolerans for lettuce growth and quality enhancement.Archives of microbiology · 2026Article
- Effects of Inorganic Fluoride and the Fluoroquinolone Antibiotic Pefloxacin on the Growth and Microbiome Structure ofInternational journal of molecular sciences · 2026Article
- Characterization of spatio-temporal variations in carposphere microbial diversity of olive in Longnan, China.World journal of microbiology & biotechnology · 2026Article
- Airborne Bacterial Communities: Diversity, Survival Strategies and Functional Roles in the Atmosphere.Environmental microbiology reports · 2026Review
- Effects of planting density and foliar fertilization on the phyllosphere microbial community of dual-purpose soybean.BMC plant biology · 2025Article
- Adaptively evolvedApplied and environmental microbiology · 2025Article
- Transgenic Maize ofMicroorganisms · 2025Article
- Multi-omics reveals novel forage advantages ofFrontiers in microbiology · 2025Article
- Weather parameters and biotic factors synergistically shape the phyllosphere microbiome of pomelo (Frontiers in plant science · 2025Article
- Temporal dynamics of walnut phyllosphere microbiota under synergistic pathogen exposure and environmental perturbation.Frontiers in microbiology · 2025Article
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Authors and funding
20 authors.
Funding
Abstract
The proficiency of phyllosphere microbiomes in efficiently utilizing plant-provided nutrients is pivotal for their successful colonization of plants. The methylotrophic capabilities of Methylobacterium/Methylorubrum play a crucial role in this process. However, the precise mechanisms facilitating efficient colonization remain elusive. In the present study, we investigate the significance of methanol assimilation in shaping the success of mutualistic relationships between methylotrophs and plants. A set of strains originating from Methylorubrum extorquens AM1 are subjected to evolutionary pressures to thrive under low methanol conditions. A mutation in the phosphoribosylpyrophosphate synthetase gene is identified, which converts it into a metabolic valve. This valve redirects limited C1-carbon resources towards the synthesis of biomass by up-regulating a non-essential phosphoketolase pathway. These newly acquired bacterial traits demonstrate superior colonization capabilities, even at low abundance, leading to increased growth of inoculated plants. This function is prevalent in Methylobacterium/Methylorubrum strains. In summary, our findings offer insights that could guide the selection of Methylobacterium/Methylorubrum strains for advantageous agricultural applications.
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