ArticleEuropean journal of dentistry2024
The Protective Role Antioxidant of Vitamin C in the Prevention of oral Disease: A Scoping Review of Current Literature.
Article in European journal of dentistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Mediterranean diet and dementia: MRI marker evidence from meta-analysis.European journal of medical research · 2025Pooled it
- Association between a novel Dietary Index for Gut Microbiota and periodontitis: a cross-sectional study.Frontiers in nutrition · 2026Article
- Vitamins in the Treatment of Periodontitis: Molecular Mechanism and Network Pharmacological Analysis.Oral health & preventive dentistry · 2025Review
- Chewing Matters: Masticatory Function, Oral Microbiota, and Gut Health in the Nutritional Management of Aging.Nutrients · 2025Review
- Association between dietary inflammatory index and periodontitis in American adults: exploring the mediating role of biological aging.Frontiers in nutrition · 2025Article
- Higher fat-soluble vitamin and phosphorus intake are associated with less dental caries among children and adolescents in the United States, NHANES 2011-2018.Frontiers in oral health · 2025Article
- Exploring the relationship between dietary index for gut microbiota and cognitive function.Frontiers in nutrition · 2025Article
- Association between the Dietary Index for Gut Microbiota and periodontitis: mediation by systemic inflammation.Frontiers in nutrition · 2025Article
- Periodontal health and metabolic status of type 1 diabetic children and adolescents.Frontiers in dental medicine · 2025Article
- Hypovitaminosis and its association with recurrent aphthous stomatitis: a comprehensive review of clinical correlations and diagnostic considerations.Frontiers in oral health · 2025Review
- Antibiofilm potential of plant extracts: inhibiting oral microorganisms andFrontiers in dental medicine · 2025Article
- A case-control study on oral health knowledge and dental behavior among individuals with developmental delays in Jordan: caregiver perspective.Frontiers in dental medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review meticulously examined the connection between vitamin C and periodontal disease, as well as the potential of vitamin C to prevent this condition. To gather relevant data, comprehensive electronic searches were conducted across various databases, including PubMed, EMBASE, Cochrane Library, and Web of Science, focusing on studies that explored the relationship between vitamin C and periodontal disease in individuals aged between 18 and above. From an initial pool of 421 articles, 14 were ultimately chosen for detailed analysis. This selection encompassed seven cross-sectional studies, two case-control studies, two cohort studies, and three randomized controlled trials. The analysis of these studies revealed a consistent negative association between vitamin C intake, as well as its levels in the blood, and the incidence of periodontal disease across all seven cross-sectional studies. This indicates that higher vitamin C intake and blood levels are linked to a decreased risk of developing periodontal disease. In the two case-control studies, individuals suffering from periodontitis were found to have both a lower intake of vitamin C and reduced levels of vitamin C in their blood compared to those without the disease, further underscoring the potential protective role of vitamin C against periodontal disease. The progression of periodontal disease was observed to be more rapid in patients with lower dietary intake or blood levels of vitamin C compared to controls. Regarding the effects of vitamin C administration as an intervention, there was an improvement noted in gingival bleeding among patients with gingivitis; however, no significant benefits were observed in cases of periodontitis, specifically concerning alveolar bone absorption. Through the meticulous examination of available studies, this systematic review underscores the notion that adequate vitamin C intake and maintaining sufficient levels of vitamin C in the blood can contribute significantly to reducing the risk of periodontal disease.
Identifiers
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Registered trials
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