Evidence map›Paper›PMID 39013433›Full record

ArticleZeitschrift fur Gastroenterologie2024

ReLink strategy in diagnosed-but-untreated hepatitis C-positive patients in Germany: report from a single center.

Sarah Lange, Christina Baehr, Nur Irem Cakman-Hinrichs, Katharina Cron, Hannah Fengels, Christina Gregor, Katrin Matschenz, Jörg Petersen, Robin Steinfurth, Albrecht Stoehr and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zeitschrift fur Gastroenterologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sarah LangeMVZ ifi-Institut GmbH an der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Christina BaehrMVZ ifi-Institut GmbH an der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Nur Irem Cakman-HinrichsMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Katharina CronMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Hannah FengelsMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Christina GregorMVZ ifi-Institut GmbH an der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Katrin MatschenzMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Jörg PetersenMVZ ifi-Institut GmbH an der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Robin SteinfurthMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamubrg, Germany.
Albrecht StoehrMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Stefan UngerMVZ ifi-Institut GmbH An der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.
Maria Gil MirFormer employee of Gilead, München, Germany.
Candido HernándezGilead Sciences Europe Ltd, Uxbridge, United Kingdom of Great Britain and Northern Ireland.
Marianna SchwenkenGilead Sciences GmbH, Martinsried, Germany.
Peter BuggischMVZ ifi-Institut GmbH an der Asklepios Klinik St. Georg, Haus L, Hamburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe ReLink project aims to reintegrate diagnosed-but-untreated hepatitis-C-positive patients into medical care and initiate a therapy. MATERIAL/

methodsA retrospective search within the practice management system of a single center in Germany identified among 1965 hepatitis-C-positive patients 100 untreated patients with available contact details and meeting all inclusion criteria. Patients were contacted by 2 contact rounds.

resultsOut of 100 patients, 64% were male. Most patients (81%) were aged between 30 and 59 years. The patients belonged to high-risk groups for hepatitis C virus infections or had other comorbidities. The majority of patients injected drugs (21%) and/or were currently or had been on substitution therapy (44%); alcohol addiction was also frequent (21%). Out of 25 patients who agreed to an appointment, 10 patients (40%) started therapy and 5 additional patients (20%) agreed to therapy but were not yet able to start or had not yet made a decision. One‑third of patients who agreed to an appointment did not show up.

conclusionsDiagnosed-but-untreated patients are an important subgroup of hepatitis-C-positive patients; their recall to the clinic for direct-acting antiviral therapy is possible. However, inaccurate contact information, unresponsiveness to outreach, and further reluctance to attend doctor appointments limited the overall impact of this program. Regular review of the patients' contact details may facilitate both follow-up and recall.

Indexed as

Antiviral AgentsAdultAgedAge DistributionFemaleGermanyHepatitis CHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsTreatment OutcomeYoung AdultAntiviral Agents

Identifiers

PMID39013433
PMCPMC11466545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.