Evidence map›Paper›PMID 39013122›Full record

ArticleJournal of proteome research2024

Metabolic and Microbial Dysregulation in Preterm Infants with Neonatal Respiratory Distress Syndrome: An Early Developmental Perspective.

Yanxu Bi, Wenyi Yu, Wenjie Bian, Mengtong Jin, Yukun He, Jinglei Wang, Xiaofeng Miao, Tiantian Guo, Xiaojun Ma, Pihua Gong and 4 more

Abstract read
In one paragraph

Article in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yanxu BiDepartment of Pediatrics, Linfen Central Hospital, Linfen 041000, China.
Wenyi YuDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
Wenjie BianDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
Mengtong JinLinfen Clinical Medicine Research Center, Linfen 041000, China.
Yukun HeDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
Jinglei WangDepartment of Pediatrics, Linfen Central Hospital, Linfen 041000, China.
Xiaofeng MiaoLinfen Clinical Medicine Research Center, Linfen 041000, China.
Tiantian GuoLinfen Clinical Medicine Research Center, Linfen 041000, China.
Xiaojun MaDepartment of Respiratory and Critical Care Medicine, Linfen Central Hospital, Linfen 041000, China.
Pihua GongDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
Ran LiDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.
Jiangli XiDepartment of Pediatrics, Linfen Central Hospital, Linfen 041000, China.
Shuming GuoLinfen Clinical Medicine Research Center, Linfen 041000, China.
Zhancheng GaoDepartment of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China.ORCID 0000-0001-7415-1416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal respiratory distress syndrome (NRDS) is one of the most severe respiratory disorders in preterm infants (PTIs) due to immature lung development. To delineate the serum metabolic alterations and gut microbiota variations in NRDS and assess their implications on neonatal development, we enrolled 13 NRDS neonates and 12 PTIs and collected fecal and serum specimens after birth. Longitudinal fecal sampling was conducted weekly for a month in NRDS neonates. NRDS neonates were characterized by notably reduced gestational ages and birth weights and a higher rate of asphyxia at birth relative to PTIs. Early postnatal disturbances in tryptophan metabolism were evident in the NRDS group, concomitant with elevated relative abundance of

Indexed as

FecesGastrointestinal MicrobiomeInfant, PrematureRespiratory Distress Syndrome, NewbornFemaleGestational AgeHumansHydrocortisoneInfant, NewbornMaleTryptophanHydrocortisoneTryptophanmelatonin synthesisneonatal respiratory distress syndromepreterm infantsprobioticstryptophan metabolism

Identifiers

PMID39013122
PMCPMC11301678

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.