Evidence map›Paper›PMID 39012870›Full record

ArticlePloS one2024

Prevalence of alcohol use by gender and HIV status in rural Uganda.

Adriane Wynn, Katelyn M Sileo, Katherine Schmarje Crockett, Rose Naigino, Michael Ediau, Rhoda K Wanyenze, Noah Kiwanuka, Natasha K Martin, Susan M Kiene

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adriane WynnDivision of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, California, United States of America.ORCID 0000-0001-8067-3616
Katelyn M SileoDepartment of Public Health, The University of Texas at San Antonio, San Antonio, Texas, United States of America.
Katherine Schmarje CrockettDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California, United States of America.
Rose NaiginoDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California, United States of America.
Michael EdiauDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California, United States of America.
Rhoda K WanyenzeDepartment of Disease Control and Environmental Health, Makerere University School of Public Health, Kampala, Uganda.
Noah KiwanukaEpidemiology and Biostatistics Department, at Makerere University School of Public Health, Kampala, Uganda.
Natasha K MartinDivision of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, California, United States of America.
Susan M KieneDivision of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, California, United States of America.ORCID 0000-0001-8922-5289

Funding

Enhanced Linkage to HIV Care Following Home-Based HIV Testing in Rural UgandaR01MH106391 · NIMH · SAN DIEGO STATE UNIVERSITY · PI KIENE, SUSAN MARIA, WANYENZE, RHODA KITTI · 2015 to 2019
$3.4M
Modeling reductions in harmful alcohol use on HIV transmission and mortality in the era of universal test and treat in UgandaK01AA027733 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WYNN, ADRIANE MICHELLE · 2020 to 2024
$888k
NIAAA NIH HHS K01 AA027733NIMH NIH HHS R01 MH106391
6 · The paper itself

Abstract

backgroundAlcohol use is a major contributor to mortality and morbidity worldwide. Uganda has a high level of alcohol use per capita. Compared to men, women are less likely to consume alcohol globally; however, women who drink have increased risks for co-occurring conditions, including depression, intimate partner violence, and HIV. This study assessed the prevalence of alcohol use and correlates of harmful alcohol use by gender and HIV status in rural Uganda.

methodsWe used cross-sectional data from a study among women and men aged 15-59 residing in rural, central Uganda and accepting home-based HIV testing (Nov 2017 to Dec 2020). We estimated the prevalence of levels of alcohol use (categorized as no alcohol use (score 0), low (score 1-3 for men; 1-2 for women), medium (score 4-5 for men; 3-5 for women), high (score 6-7), and very-high (score 8-12) use with the AUDIT-C), stratified by gender and HIV status. We assessed correlates of harmful alcohol use using multivariable logistic regression models for women and men.

resultsAmong 18,460 participants, 67% (95% CI: 66-67%) reported no alcohol use, 16% (95% CI: 16-17%) reported low, 5% (95% CI: 4.8-5%) reported medium, 5% (95% CI: 4-5%) reported high, and 3% (95% CI: 2.8-3) reported very high alcohol use. Compared to women, men were more likely to report alcohol use (Chi-squared p-value<0.0001). People diagnosed with HIV (both newly diagnosed and previously aware of their status prior to home-based HIV testing) were more likely to report low, medium, high, and very high alcohol use compared to those who were HIV negative (Chi-squared p-value<0.0001). Among women, those who were newly diagnosed were more likely report alcohol use, compared to those who were HIV negative. In multivariable models, being newly diagnosed with HIV (compared to HIV negative) increased the odds of harmful alcohol use among women, but not men.

conclusionWhile alcohol use was higher among men and people living with HIV, being newly diagnosed with HIV had a stronger relationship with harmful alcohol use among women than men. More research is needed to understand how alcohol use may increase the risks of HIV acquisition among women and to identify gender-responsive services to address harmful alcohol use and increase access to HIV testing and linkage to care for women who use harmful levels of alcohol.

Indexed as

Alcohol DrinkingHIV InfectionsRural PopulationAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceSex FactorsUgandaYoung Adult

Identifiers

PMID39012870
PMCPMC11251619

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.