Evidence map›Paper›PMID 39012848›Full record

ArticlePLoS neglected tropical diseases2024

A sero-epidemiological analysis of Coxiella burnetii infection and its risk factors in livestock from Addis Ababa, Adama, and Modjo abattoirs and pastoral areas of Oromia, Ethiopia.

Ashenafi Milkesa, Tesfaye Rufael, Getachew Kinfe, Redeat Belaineh, Abdella Bulbula, Donghee Cho, Mohammed Naimuddin, Teshale Sori, Hunduma Dinka

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Article in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ashenafi MilkesaDepartment of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Tesfaye RufaelAnimal Health Institute (AHI), Sebeta, Ethiopia.
Getachew KinfeAnimal Health Institute (AHI), Sebeta, Ethiopia.
Redeat BelainehAnimal Health Institute (AHI), Sebeta, Ethiopia.
Abdella BulbulaAnimal Health Institute (AHI), Sebeta, Ethiopia.
Donghee ChoDepartment of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Mohammed NaimuddinDepartment of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.
Teshale SoriDepartment of Clinical Studies, College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia.
Hunduma DinkaDepartment of Applied Biology, School of Applied Natural Science, Adama Science and Technology University, Adama, Ethiopia.ORCID 0000-0002-3498-7689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoxiella burnetii is causing infections in both humans and animals, resulting in Q fever and Coxiellosis, respectively. Information on the occurrence of C. burnetii infection is scarce in Ethiopia. This study estimated the sero-prevalence of C. burnetii infection and associated risk factors in four common livestock species from Addis Ababa, Adama, and Modjo abattoirs and pastoral areas of Oromia, Ethiopia. RESULTS/PRINCIPAL

findingsSera samples were analyzed for the presence of anti-C. burnetii antibodies using an indirect Enzyme Linked Immunosorbent Assay kit. Out of the 4140 serum samples tested, 777 (18.77%; 95% CI: 17.59, 19.99) were found positive for C. burnetii. The sero-prevalence estimate was 27.17% at Addis Ababa abattoir, 19.41% at Adama abattoir, 19.13% at Modjo abattoir and 12.1% in animals tested from pastoral areas. Sera analysis at the animal species level showed that cattle exhibited the lowest sero-prevalence estimate (11.83%; 95% CI, 10.27-13.53%), while the highest was observed in camels (28.39%; 95% CI, 25.16-31.80%). The sero-prevalence estimate was 21.34% (95% CI, 18.86-23.99%) in goats and 20.17% (95% CI, 17.49-23.07%) in sheep. The results of multivariable logistic regression analysis showed that species, age, sex of animals and tick infestation were important risk factors for C. burnetii infection. The odds of infection were 3.22 times higher in camels and almost twice as high in goats and sheep compared to cattle. Adult animals were infected more likely (OR = 3.23) than young ones. Interestingly, a significant difference was observed in the sero-prevalence of infection between animals that were infested with ticks (OR = 16.32) and those which were tick-free.

conclusionThis study provides valuable insights into the sero-epidemiology of C. burnetii infection in four common livestock species at major abattoirs and pastoral areas of Ethiopia. The findings highlight the need for further studies and implementing surveillance and biosecurity measures to prevent the spread of the disease in both humans and livestock to safeguard the economical and public health aspects.

Indexed as

AbattoirsAntibodies, BacterialCamelusCattle DiseasesCoxiella burnetiiGoat DiseasesGoatsLivestockQ FeverAnimalsCattleEthiopiaFemaleMalePrevalenceRisk FactorsAntibodies, Bacterial

Identifiers

PMID39012848
PMCPMC11251603

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