Evidence map›Paper›PMID 39012405›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Effect of exercise on fatigue and depression in breastcancer women undergoing chemotherapy: a systematic review and meta-analysis.

Muhammad Hamza Sikandari, Aisha Siddiqui, Menhas Ahmad, Samiullah Shaikh, Sundal Khuwaja, Faraz Ahmad, Abdul Rehman Saleem, Kumar Sanjay, Mahesh Kumar, Sumble Memon and 2 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle-tumor metabolic competition.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Muhammad Hamza SikandariInternal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College Lyari Karachi, , H#565-66F/46, Khokhar Mohallah, Hyderabad, Pakistan. hamza103950@gmail.com.
Aisha SiddiquiInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Menhas AhmadInternal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan.
Samiullah ShaikhInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Sundal KhuwajaInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Faraz AhmadInternal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan.
Abdul Rehman SaleemInternal Medicine, Shaheed Mohtarma Benazir Bhutto Medical College, Lyari, Karachi, Pakistan.
Kumar SanjayInternal Medicine, Isra University Hyderbad, Hyderabad, Pakistan.
Mahesh KumarInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Sumble MemonInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
Ghulam Qadir NooraniInternal Medicine, Chandka Medical University Larkana (SMBBMU), Larkana, Pakistan.
Farina Fatima SiddiquiInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This meta-analysis examined the effectiveness of exercise interventions in reducing fatigue and depression among women undergoing chemotherapy for breast cancer. The study followed PRISMA guidelines and analysed seven randomized controlled trials between 2016 and 2022. The results showed that exercise can substantially reduce fatigue levels (MD: -0.40, CI: -0.66, -0.14, P: 0.003), a common side effect of chemotherapy. Although depression did not significantly change (MD: -0.39, CI: -0.98, 0.20, P: 0.19), this study highlights the positive impact of exercise on mental health outcomes. The control group also experienced decreased quality of life (MD: 0.18, CI: 0.01-0.35, P: 0.03), emphasizing the importance of incorporating exercise interventions to improve overall well-being during breast cancer treatment. In addition to primary outcomes, the study revealed that exercise positively affected secondary aspects such as cognitive fatigue, social function, physical function, constipation, and dyspnoea.

Indexed as

Breast NeoplasmsDepressionFatigueQuality of LifeRandomized Controlled Trials as TopicAntineoplastic AgentsExerciseExercise TherapyFemaleHumansAntineoplastic AgentsBreast CancerChemotherapyDepressionFatigueQuality of Life(QOL)

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.