Evidence map›Paper›PMID 39012147›Full record

ArticlemBio2024

Catabolism of β-5 linked aromatics by

Fletcher Metz, Abigail M Olsen, Fachuang Lu, Kevin S Myers, Marco N Allemann, Joshua K Michener, Daniel R Noguera, Timothy J Donohue

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. UsingACS ES&T engineering · 2026
    Article
  5. mSystems · 2025
    Article
  6. Article
  7. Transcriptomic data sets forMicrobiology resource announcements · 2025
    Article
  8. Obtaining PDC and other high-added value products from lignin byJournal of integrative bioinformatics · 2025
    Article
  9. Using DNA affinity purification sequencing (DAP-seq) to identifyMicrobiology resource announcements · 2025
    Article
  10. Article
  11. Article
  12. RB-TnSeq barcode abundance data sets forMicrobiology resource announcements · 2025
    Article
  13. Transcriptomic data sets forMicrobiology resource announcements · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fletcher MetzDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0001-7263-051X
Abigail M OlsenDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.
Fachuang LuDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.
Kevin S MyersDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0003-3302-3877
Marco N AllemannBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.
Joshua K MichenerBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee, USA.ORCID 0000-0003-2302-8180
Daniel R NogueraDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.
Timothy J DonohueDOE Great Lakes Bioenergy Research Center, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0001-8738-2467

Funding

PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM007133 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI PERNA, NICOLE T · 1985 to 2023
$16.5M
HHS | National Institutes of Health (NIH) Training Grant #5T32GM007133NIGMS NIH HHS T32 GM007133U.S. Department of Energy (DOE) DE-SC0018409U.S. Department of Energy (DOE) Early Career Award to Joshua K. Michener
6 · The paper itself

Abstract

Aromatic compounds are an important source of commodity chemicals traditionally produced from fossil fuels. Aromatics derived from plant lignin can potentially be converted into commodity chemicals through depolymerization followed by microbial funneling of monomers and low molecular weight oligomers. This study investigates the catabolism of the β-5 linked aromatic dimer dehydrodiconiferyl alcohol (DC-A) by the bacterium IMPORTANCE: In the transition to a circular bioeconomy, the plant polymer lignin holds promise as a renewable source of industrially important aromatic chemicals. However, since lignin contains aromatic subunits joined by various chemical linkages, producing single chemical products from this polymer can be challenging. One strategy to overcome this challenge is using microbes to funnel a mixture of lignin-derived aromatics into target chemical products. This approach requires strategies to cleave the major inter-unit linkages of lignin to release monomers for funneling into valuable products. In this study, we report newly discovered aspects of a pathway by which the

Indexed as

Metabolic Networks and PathwaysSphingomonadaceaeBacterial ProteinsHydrocarbons, AromaticLigninBacterial ProteinsHydrocarbons, AromaticLigninaromatic compoundsbiotechnologyenzymesgeneticsgenomicsligninolysis

Identifiers

PMID39012147
PMCPMC11323797

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.