Evidence map›Paper›PMID 39011877›Full record

ArticleJournal of surgical oncology2024

Preoperative chemotherapy response and survival in patients with colorectal cancer peritoneal metastases.

Nadina Tinsley, Sarah T O'Dwyer, Raghavendar Nagaraju, Bipasha Chakrabarty, Michael Braun, Saifee Mullamitha, Konstantinos Kamposioras, F E Marti Marti, Mark Saunders, Hamish Clouston and 6 more

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Development ofDrug delivery and translational research · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Nadina TinsleyDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0003-1877-658X
Sarah T O'DwyerDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Raghavendar NagarajuDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Bipasha ChakrabartyChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Michael BraunChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Saifee MullamithaChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Konstantinos KamposiorasChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
F E Marti MartiChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Mark SaundersDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Hamish CloustonChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Chelliah SelvasekarChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Jonathan WildChristie Peritoneal Oncology Centre (CPOC) at The Christie NHS Foundation Trust, Manchester, UK.
Malcolm WilsonDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Andrew RenehanDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Omer AzizDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Jorge BarriusoDivision of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment guidelines provided by PRODIGE-7 recommend perioperative systemic chemotherapy before cytoreductive surgery (CRS) for colorectal cancer peritoneal metastases (CRPM). Toxicity with multimodal treatment needs to be better defined. Chemotherapy response and impact on survival have not been reported. We assessed CRPM patients who received systemic oxaliplatin/irinotecan before CRS (preoperative) with Mitomycin C (35 mg/m

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsColorectal NeoplasmsHyperthermic Intraperitoneal ChemotherapyPeritoneal NeoplasmsAdultAgedCytoreduction Surgical ProceduresFemaleHumansIrinotecanMaleMiddle AgedMitomycinOxaliplatinPreoperative CareProspective StudiesIrinotecanMitomycinOxaliplatinchemotherapy responsecolorectal cancer peritoneal metastases

Identifiers

PMID39011877
PMCPMC11826003

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.