Evidence map›Paper›PMID 39011811›Full record

ArticleAdvanced healthcare materials2024

Surface-Grafted Biocompatible Polymer Conductors for Stable and Compliant Electrodes for Brain Interfaces.

Rachel Blau, Samantha M Russman, Yi Qie, Wade Shipley, Allison Lim, Alexander X Chen, Audithya Nyayachavadi, Louis Ah, Abdulhameed Abdal, Guillermo L Esparza and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. PEDOT:PSS-A Key Material for Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Rachel BlauAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.ORCID 0000-0002-1285-8894
Samantha M RussmanDepartment of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Yi QieAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Wade ShipleyMaterials Science and Engineering Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0418, USA.
Allison LimAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Alexander X ChenAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Audithya NyayachavadiAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Louis AhAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Abdulhameed AbdalDepartment of Mechanical and Aerospace Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Guillermo L EsparzaAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Samuel J EdmundsDepartment of Electrical and Computer Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Ritwik VatsyayanDepartment of Electrical and Computer Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Sean P DunfieldAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Moumita HalderAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Jesse V JokerstAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
David P FenningAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Andrea R TaoAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Shadi A DayehDepartment of Bioengineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.
Darren J LipomiAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0448, USA.ORCID 0000-0002-5808-7765

Funding

Thin, High-Density, High-Performance, Depth and Surface Microelectrodes for Diagnosis and Treatment of EpilepsyUG3NS123723 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2021 to 2025
$9.5M
Bringing Light to Functional Mapping in Resective NeurosurgeryDP2EB029757 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2019 to 2019
$2.4M
Integration of High Definition Display Technologies with Platinum Nanorod Microelectrodes for Large Scale in-vivo Recording and StimulationR01NS123655 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAYEH, SHADI · 2021 to 2021
$2.0M
Air Force Office of Scientific Research FA9550-19-1-0278Alfred P. Sloan FoundationBRAIN Initiative R01NS123655-01BRAIN Initiative UG3NS123723-01H2020 Marie Skłodowska-Curie Actions 898571Kuwait Foundation for the Advancement of SciencesNational Institutes of Health's Brain ResearchNational Science Foundation 1845683National Science Foundation DMR-2011924National Science Foundation DMR-2011967National Science Foundation ECCS-1542148National Science Foundation Disability and Rehabilitation Engineering CBET-2223566National Science Foundation Major Research Instrumentation Program CHE-1338173Natural Sciences and Engineering Research Council of CanadaNIBIB NIH HHS DP2 EB029757NIBIB NIH HHS DP2-EB029757NINDS NIH HHS R01 NS123655NINDS NIH HHS UG3 NS123723UC Irvine Materials Research InstituteUC President's Dissertation Year Fellowship
6 · The paper itself

Abstract

Durable and conductive interfaces that enable chronic and high-resolution recording of neural activity are essential for understanding and treating neurodegenerative disorders. These chronic implants require long-term stability and small contact areas. Consequently, they are often coated with a blend of conductive polymers and are crosslinked to enhance durability despite the potentially deleterious effect of crosslinking on the mechanical and electrical properties. Here the grafting of the poly(3,4 ethylenedioxythiophene) scaffold, poly(styrenesulfonate)-b-poly(poly(ethylene glycol) methyl ether methacrylate block copolymer brush to gold, in a controlled and tunable manner, by surface-initiated atom-transfer radical polymerization (SI-ATRP) is described. This "block-brush" provides high volumetric capacitance (120 F cm

Indexed as

Biocompatible MaterialsPolymersAnimalsBrainBrain-Computer InterfacesElectric ConductivityElectrodesGoldPolyethylene GlycolsSurface PropertiesBiocompatible MaterialsGoldPolyethylene GlycolsPolymersneural interfacePEDOTpolymer brushesself‐assemblySI‐ATRP

Identifiers

PMID39011811
PMCPMC11582513

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.