Evidence map›Paper›PMID 39011578›Full record

ArticleAndrology2025

Chronic pelvic pain among transgender men and gender diverse adults assigned female at birth.

Diana M Tordoff, Mitchell R Lunn, Annesa Flentje, Diana Atashroo, Bertha Chen, Zubin Dastur, Micah E Lubensky, Matthew Capriotti, Juno Obedin-Maliver

Abstract read
In one paragraph

Article in Andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Burden of Lower Urinary Tract and Genital Symptoms in Young Transgender Men: Prevalence and Impact on Daily Life.International journal of urology : official journal of the Japanese Urological Association · 2026
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Diana M TordoffThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.ORCID 0000-0002-9238-9927
Mitchell R LunnThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.
Annesa FlentjeThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.
Diana AtashrooDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, USA.
Bertha ChenDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Palo Alto, California, USA.
Zubin DasturThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.
Micah E LubenskyThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.
Matthew CapriottiThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.
Juno Obedin-MaliverThe PRIDE Study/PRIDEnet, Stanford University School of Medicine, Palo Alto, California, USA.

Funding

UCSF-Kaiser Urological Epidemiology Research Career Development ProgramK12DK111028 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, ALISON · 2016 to 2025
$5.3M
Gene expression outcomes in interventions for substance using HIV+ minority menK23DA039800 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLENTJE, ANNESA · 2015 to 2019
$1.0M
Mentoring the next generation of substance use, HIV, and epigenetic researchers in sexual and gender minority healthK24DA057874 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Annesa Flentje · 2023 to 2026
$793k
National Institute of Diabetes, Digestive, and Kidney Disorders K12DK111028NIDA NIH HHS K23 DA039800NIDA NIH HHS K23DA039800NIDA NIH HHS K24 DA057874NIDA NIH HHS K24DA057874NIDDK NIH HHS K12 DK111028NIH HHSPatient-Centered Outcomes Research Institute(PCORI) Award PPRN-1501-26848Stanford University School of Medicine Department of Obstetrics and Gynecology
6 · The paper itself

Abstract

backgroundThere are limited data on pelvic pain among transgender men and gender diverse people, and the impact of testosterone on pelvic pain is poorly understood.

objectiveCharacterize the prevalence and correlates of chronic pelvic pain (CPP) among transgender men and gender diverse people and examine the association between testosterone use and CPP. MATERIALS AND

methodsWe used 2020-2022 data from The Population Research in Identity and Disparities for Equality (PRIDE) Study, an online prospective cohort study of sexual and gender minority adults in the United States, to conduct complementary cross-sectional and longitudinal analyses. Our primary outcome was self-reported CPP lasting 3 months or longer measured using the Michigan Body Map.

resultsAmong 2579 transgender men and gender diverse people assigned female at birth included in our sample, 457 (18%) reported CPP. CPP correlates included: inflammatory bowel disease, irritable bowel syndrome (IBS), kidney stones, pelvic inflammatory disease, polycystic ovary syndrome (PCOS), uterine fibroids, current hormonal intrauterine device use, prior pregnancy, vaginal delivery, hysterectomy, and oophorectomy. Individuals with CPP reported a high prevalence of IBS (37%), PCOS (20%), uterine fibroids (9%), post-traumatic stress disorder (51%), and severe depression and anxiety symptoms (42% and 25%, respectively). Current testosterone use was associated with a 21% lower prevalence of CPP (adjusted prevalence ratio (aPR) 0.79, 95% confidence interval [CI]: 0.65-0.96). In longitudinal analyses (N = 79), 15 (19%) participants reported any CPP after initiating testosterone: eight (56%) of whom reported CPP prior to testosterone initiation, and seven (47%) who reported new-onset CPP. DISCUSSION AND

conclusionsThe relationship between CPP and testosterone is complex. Although testosterone use was associated with a lower prevalence of CPP, some transgender and gender diverse individuals experienced new-onset pelvic pain after testosterone initiation. Given the significant impact that CPP can have on mental health and quality of life, future research must examine the role of testosterone in specific underlying etiologies of CPP and identify potential therapies.

Indexed as

Chronic PainPelvic PainTestosteroneTransgender PersonsAdultCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalenceProspective StudiesUnited StatesYoung AdultTestosteronechronic pelvic paingender‐affirming caretestosteronetransgender

Identifiers

PMID39011578
PMCPMC11735687

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.