Evidence map›Paper›PMID 39011355›Full record

ArticleJournal of pharmaceutical policy and practice2024

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit.

Fatima Khalifa Al-Sulaiti, Dania Alkhiyami, Eman Zeyad I Elmekaty, Ahmed Awaisu, Nadir Kheir, Ahmed El-Zubair, Hend Khalifa Al-Sulaiti

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fatima Khalifa Al-SulaitiClinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.ORCID https://orcid.org/0000-0002-4305-9614
Dania AlkhiyamiClinical Pharmacy Department, Al-Wakrah Hospital, Hamad Medical Corporation, Doha, Qatar.
Eman Zeyad I ElmekatyClinical Pharmacy Department, Communicable Disease Center, Hamad Medical Corporation, Doha, Qatar.
Ahmed AwaisuClinical Pharmacy and Practice Department, College of Pharmacy, QU Health, Qatar University, Doha, Qatar.ORCID https://orcid.org/0000-0002-9029-8925
Nadir KheirCollege of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates.
Ahmed El-ZubairClinical Pharmacy Department, Al-Khor Hospital, Hamad Medical Corporation, Doha, Qatar.
Hend Khalifa Al-SulaitiClinical Pharmacy Department, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The use of gentamicin in the treatment of infectious diseases requires frequent monitoring to attain the best treatment outcomes. Objective: This study aimed to evaluate the appropriateness of gentamicin therapeutic drug monitoring (TDM) at a tertiary care hospital in Qatar. Methods: A one-year quantitative retrospective chart review of all gentamicin TDM records was conducted. Evidence-based criteria were applied to evaluate the appropriateness of gentamicin TDM in terms of indication, sampling times, and post-analytical actions. Results: Out of 59 captured gentamicin TDM records, 58 gentamicin samples were eligible for evaluation. Overall, gentamicin TDM appropriateness was achieved in 50% ( Conclusion: Suboptimal gentamicin TDM practices exist in relation to sampling time and post-analytical actions. Studies exploring setting-specific reasons behind inappropriate TDM practices and methods of its optimisation are needed.

Indexed as

aminoglycosidesantibioticsauditclinical pharmacokineticsgentamicinqualityTherapeutic drug monitoring

Identifiers

PMID39011355
PMCPMC11249166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.