Evidence map›Paper›PMID 39011249›Full record

ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2024

Adult People with Hemophilia A Have Low Annualized Bleeding Rate, However the Arthropathy Remains a Burden: A Retrospective Cohort Study.

Eréndira Pacheco Zavala, Carlos Vargas Oliva, Karla Edith Santibañez Bedolla, Blanca Olivia Murillo Ortíz, Octavio Martínez Villegas, Lauro Fabián Amador Medina

Abstract read
In one paragraph

Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eréndira Pacheco ZavalaHigh Specialty Medical Unit UMAE No.1, Bajio, Mexican Institute of Social Security, Leon, Guanajuato, Mexico.ORCID https://orcid.org/0009-0007-1388-326X
Carlos Vargas OlivaDepartment of Medicine and Nutrition, University of Guanajuato, Leon, Guanajuato, Mexico.ORCID https://orcid.org/0009-0007-3590-1246
Karla Edith Santibañez BedollaDepartment of Medicine and Nutrition, University of Guanajuato, Leon, Guanajuato, Mexico.ORCID https://orcid.org/0000-0002-7313-3109
Blanca Olivia Murillo OrtízClinical Epidemiology Research Unit, OOAD Guanajuato, Mexican Institute of Social Security, Blvd. Adolfo López Mateos Esq Paseo de los Insurgentes S/N, Los Paraisos, 37320 Leon, Guanajuato, Mexico.ORCID https://orcid.org/0000-0003-4775-2755
Octavio Martínez VillegasHigh Specialty Medical Unit, Hospital of Gynecology and Pediatrics No. 48, Mexican Institute of Social Security, Leon, Guanajuato, Mexico.ORCID https://orcid.org/0000-0001-8881-1104
Lauro Fabián Amador MedinaClinical Epidemiology Research Unit, OOAD Guanajuato, Mexican Institute of Social Security, Blvd. Adolfo López Mateos Esq Paseo de los Insurgentes S/N, Los Paraisos, 37320 Leon, Guanajuato, Mexico.ORCID 0000-0003-4900-4726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital Hemophilia A is a complex disease to treat, especially in places without access to hemophilia treatment centers (HTCs). The primary aim of this study was to analyze the outcomes of a cohort of adult people with congenital hemophilia A in an HTC localized in the Bajio region of Mexico. Observational retrospective study of a cohort of 82 adult people with congenital hemophilia A treated in a tertiary-level hospital in the Bajio region of Mexico, between June 2022 and June 2023. The median age of the patients was 29.5 years, 60.9% with severe hemophilia A, 53.6% were under some factor VIII prophylaxis regimen, and 52.4% had home therapy. The median annualized bleeding rate (ABR) was one bleed/year (IQR 0-3 bleeds/year) including a median of zero joint bleeds/year (IQR 0-3 bleeds/year). The presence of high-response inhibitors was detected in 8.5%, with an overall incidence of inhibitors of 14.6% of the cohort. Univariate analysis showed that inhibitors (OR 21.10; CI 95% 1.20-370.3;

Indexed as

Annualized bleeding rateHemophilia AHemophilia Treatment CenterHemophilic arthropathyPeople with hemophilia

Identifiers

PMID39011249
PMCPMC11246366

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.