Evidence map›Paper›PMID 39011146›Full record

ArticleFrontiers in microbiology2024

Sub-MIC antibiotics increased the fitness cost of CRISPR-Cas in

Ting Yu, Jiayuan Huang, Xinyue Huang, Jingchen Hao, Pengyu Zhang, Tingting Guo, Guangyu Bao, Guocai Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Whole-genome sequencing ofMicrobial genomics · 2025
    Article
  3. Comprehensive Approaches to CombattingAntibiotics (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ting Yu *Department of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Jiayuan Huang *Department of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Xinyue HuangDepartment of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Jingchen HaoDepartment of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Pengyu ZhangDepartment of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Tingting GuoDepartment of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.
Guangyu BaoDepartment of Laboratory Medicine, Affiliated Hospital, Yangzhou University, Yangzhou, China.
Guocai LiDepartment of Microbiology, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The escalating prevalence of bacterial resistance, particularly multidrug-resistant bacteria like Methods and Results: In the study, we conducted in vitro competition experiments to investigate the influence of sub-minimum inhibitory concentration (sub-MIC) on the CRISPR-Cas systems' fitness cost in Conclusion: Our findings suggest that the I-Fb CRISPR-Cas system confers a significant competitive advantage in

Indexed as

Acinetobacter baumanniiCRISPR-Casfitness costmetabolomicssub-MIC

Identifiers

PMID39011146
PMCPMC11246858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.