Evidence map›Paper›PMID 39010889›Full record

ArticleERJ open research2024

Altered circadian gene expression in primary human airway epithelial cells in asthma.

Weston T Powell, Lindsay V Clark, Lucille M Rich, Elizabeth R Vanderwall, Camille Gates, Maria P White, Jason S Debley

Abstract read
In one paragraph

Article in ERJ open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Frequent exacerbator-a novel endotype of pediatric asthma.The Journal of allergy and clinical immunology · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Weston T PowellCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-1555-1425
Lindsay V ClarkCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.
Lucille M RichCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0001-8109-1028
Elizabeth R VanderwallCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.ORCID https://orcid.org/0000-0002-5684-3694
Camille GatesCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.
Maria P WhiteCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.
Jason S DebleyCenter for Respiratory Biology and Therapeutics, Seattle Children's Research Institute, Seattle Children's Hospital, Department of Pediatrics, Pulmonary and Sleep Medicine, University of Washington, Seattle, WA, USA.

Funding

The Bioinformatics and Data Management Core (BDMC)U19AI175089 · NIAID · UNIVERSITY OF WASHINGTON · PI JASON S DEBLEY, Teal S Hallstrand · 2023 to 2026
$7.8M
Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodelingR01AI163160 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI JASON S DEBLEY · 2022 to 2026
$4.3M
Impact of Heterogeneous Airway Epithelial ACE2 Expression and Interferon Responses on SARS-CoV2 Infectivity and ReplicationK24AI150991 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI DEBLEY, JASON S · 2020 to 2024
$1.2M
NIAID NIH HHS K24 AI150991NIAID NIH HHS R01 AI163160NIAID NIH HHS U19 AI175089
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39010889
PMCPMC11247365

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.