Evidence map›Paper›PMID 39010827›Full record

ArticleBioanalysis2024

Mitigating target interference challenges in bridging immunogenicity assay to detect anti-tocilizumab antibodies.

Kamala Bhavaraju, Mamta Kumari Dhiman, Hema Desai, Kyla O' Brien, Sagarika Sunil Gadgil, Soumyaranjan Mohapatra, Vikas Kumar

Abstract read
In one paragraph

Article in Bioanalysis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kamala BhavarajuClinical Bioanalytics, Biological Sciences, Biologics, Dr. Reddy's Laboratories Ltd., 8-2-337, Road No.3, Banjara Hills, Hyderabad 500034, Telangana, India.ORCID 0009-0005-1855-5316
Mamta Kumari DhimanClinical Bioanalytics, Biological Sciences, Biologics, Dr. Reddy's Laboratories Ltd., 8-2-337, Road No.3, Banjara Hills, Hyderabad 500034, Telangana, India.ORCID 0009-0002-9310-3043
Hema DesaiClinical Pharmacology and Bioanalysis, Syneos Health, Princeton, NJ 08540, USA.ORCID 0009-0006-5911-8662
Kyla O' BrienClinical Pharmacology and Bioanalysis, Syneos Health, Princeton, NJ 08540, USA.ORCID 0009-0005-5389-5359
Sagarika Sunil GadgilClinical Bioanalytics, Biological Sciences, Biologics, Dr. Reddy's Laboratories Ltd., 8-2-337, Road No.3, Banjara Hills, Hyderabad 500034, Telangana, India.ORCID 0009-0004-2034-2507
Soumyaranjan MohapatraClinical Bioanalytics, Biological Sciences, Biologics, Dr. Reddy's Laboratories Ltd., 8-2-337, Road No.3, Banjara Hills, Hyderabad 500034, Telangana, India.ORCID 0009-0005-2061-1719
Vikas KumarClinical Bioanalytics, Biological Sciences, Biologics, Dr. Reddy's Laboratories Ltd., 8-2-337, Road No.3, Banjara Hills, Hyderabad 500034, Telangana, India.ORCID 0000-0002-9344-6073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, Monoclonal, HumanizedAntibodiesHumansImmunoassayInterleukin-6AntibodiesAntibodies, Monoclonal, HumanizedInterleukin-6tocilizumabanti-drug antibodieselectrochemiluminescenceserum IL-6serum IL-6 receptortocilizumabvalidation

Identifiers

PMID39010827
PMCPMC11352699

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.