Evidence map›Paper›PMID 39010826›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2024

Chronic hyperglycemia aggravates lung function in a

Guiying Cui, Dina A Moustafa, Shilin Zhao, Analia Vazquez Cegla, James T Lyles, Joanna B Goldberg, Joshua D Chandler, Nael A McCarty

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guiying CuiDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.ORCID 0000-0002-7336-6076
Dina A MoustafaDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
Shilin ZhaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States.ORCID 0000-0002-3921-3965
Analia Vazquez CeglaDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
James T LylesDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
Joanna B GoldbergDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.
Joshua D ChandlerDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.ORCID 0000-0003-3211-7935
Nael A McCartyDivision of Pulmonology, Asthma, Cystic Fibrosis, and Sleep, Department of Pediatrics, Emory + Children's Center for Cystic Fibrosis and Airways Disease Research, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia, United States.ORCID 0000-0002-4648-3912

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Neutrophil hyperexocytosis and hypochlorous acid exposure in early cystic fibrosis lung diseaseR01HL150658 · NHLBI · EMORY UNIVERSITY · PI Joshua D Chandler · 2023 to 2026
$1.5M
Illumina NovaSeq 6000 High Throughput DNA Sequencer for Emory UniversityS10OD026799 · OD · EMORY UNIVERSITY · PI BOSINGER, STEVEN EDWARD · 2019 to 2019
$985k
Cystic Fibrosis Foundation (CFF) MCCART21G0Cystic Fibrosis Foundation (CFF) MCCART21P0HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01 HL 150658NHLBI NIH HHS R01 HL150658NIH HHS P51 OD011132NIH HHS S10 OD026799
6 · The paper itself

Abstract

Cystic fibrosis-related diabetes (CFRD), the most common comorbidity in cystic fibrosis (CF), leads to increased mortality by accelerating the decline in lung function.

Indexed as

Diabetes Mellitus, ExperimentalEpithelial Sodium ChannelsHyperglycemiaLungMice, TransgenicAnimalsBronchoalveolar Lavage FluidCystic FibrosisDisease Models, AnimalMaleMiceNeutrophilsEpithelial Sodium ChannelsScnn1b protein, mousecystic fibrosis-related diabeteslung infectionPseudomonas aeruginosastreptozotocin

Identifiers

PMID39010826
PMCPMC11482466

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.