Evidence map›Paper›PMID 39010675›Full record

ArticleACR open rheumatology2024

Leveraging Habits to Improve Adherence to Gout Medications: A Qualitative Study.

Katherine L Crum, Niteesh K Choudhry, Constance Fontanet, Ellen S Sears, Kaitlin Hanken, Julie C Lauffenburger, Julianna Mastrorilli, Theresa Oduol, Seanna Vine, Gauri Bhatkhande and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACR open rheumatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Katherine L CrumBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-0074-0645
Niteesh K ChoudhryBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Constance FontanetGeisel School of Medicine at Dartmouth College, Hanover, New Hampshire, USA.
Ellen S SearsAnalysis Group, NYC, NY, USA.
Kaitlin HankenBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Julie C LauffenburgerBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-4940-4140
Julianna MastrorilliBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Theresa OduolBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Seanna VineBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Gauri BhatkhandeBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Rebecca OranBlue Cross Blue Shield of Massachusetts, Boston.
Ted Robertsonideas42, New York City, New York.
Wendy WoodUniversity of Southern California, Los Angeles.
Candace H FeldmanBrigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.ORCID https://orcid.org/0000-0002-4980-9770

Funding

The Roybal Center for TherapeuticOptimization using BehavioralScienceP30AG064199 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI Julie Christine Lauffenburger · 2019 to 2026
$8.3M
NIA NIH HHS P30 AG064199NIH HHS NIH P30AG064199
6 · The paper itself

Abstract

objectiveThis study investigates patients' medication-taking routines and the feasibility of harnessing habit formation through context cues and rewards to improve medication adherence.

methodsSemistructured qualitative interviews with patients with gout from an urban health care system were conducted to explore typical medication-taking behavior, experiences using electronic pill bottles, barriers to adherence, existing context cues, and potential cues and rewards for habit-forming behavior. Medication-taking patterns were recorded for six weeks using electronic pill bottles before interviews to inform discussion. Transcribed interviews were analyzed to generate themes using codes developed by the study team, with representative quotations selected as illustrations.

resultsWe conducted interviews with 15 individuals (mean age 60.6 [SD 20.3] years, three women [20%], and nine White patients [60%]). Pill bottle-recorded adherence to urate-lowering therapy (ULT) was high (mean 0.91 [SD 0.10]), and one patient was experiencing an active gout flare. Five key themes emerged: (1) reasons for nonadherence, (2) internal and external motivations for adherence, (3) structured routines around taking medications, (4) rewards for good medication adherence, and (5) the role of pill cap technology in medication-taking.

conclusionThe importance of a predictable, structured routine in which participants could incorporate their medication-taking behavior emerged as a key factor that promoted consistent adherence. Further, identifying context cues and reminders seemed to promote incorporation of medication-taking into routines. Therefore, habit-based interventions that use context cues to establish routines around medication-taking may be a feasible strategy to improve adherence in patients with chronic conditions such as gout.

Identifiers

PMID39010675
PMCPMC11471940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.