ArticleBMC musculoskeletal disorders2024
Association of MRI findings with paraspinal muscles fat infiltration at lower lumbar levels in patients with chronic low back pain: a multicenter prospective study.
Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Paraspinal muscle quality in chronic low back pain: a systematic review and meta-analysis of muscle atrophy and fat infiltration.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Pooled it
- The Association Between Lumbar Disc Degeneration and Paraspinal Muscle Morphology: The Role of Age in a Quantitative Magnetic Resonance Imaging-Based Study.Biomedicines · 2026Article
- Clinical significance and future applications of standardized imaging parameters for assessing paraspinal muscle fatty infiltration in lumbar degenerative disease: a narrative review.Journal of orthopaedic surgery and research · 2026Review
- Deep learning-based assessment of paraspinal muscle degeneration and its relationships to muscle function and disability outcomes in chronic low back pain: a prospective study.European radiology · 2026Article
- An Observational Study of Human Umbilical Cord Tissue Allografts for Paraspinal Muscle and Entheses Defects in the Thoracic and Lumbar Regions.Biomedicines · 2026Article
- Association between body roundness index and the prevalence of diffuse idiopathic skeletal hyperostosis in elderly patients: the Bunkyo health study.Scientific reports · 2026Article
- Cellular and molecular mechanisms of fatty infiltration in paraspinal muscles in spine-specific sarcopenia.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Review
- Pathophysiology, diagnosis, and management of discogenic low back pain: a phenotype-driven precision framework for surgical and interventional decision-making.Frontiers in surgery · 2026Review
- MRI Analysis of Paraspinal Muscle Morphology in Patients With Chronic Low Back Pain: A Case-Control Study.Cureus · 2025Article
- Interlimb differences in gait kinematics, kinetics, and muscle activation during walking and running one year after acute unilateral Achilles tendon rupture.Journal of orthopaedic surgery and research · 2025Article
- Article
- Integrative Postural Rehabilitation for Kyphotic Deformity in a Patient with Parkinson's Disease: A Case Report and Literature Review.Journal of clinical medicine · 2025Article
- Qualitative and quantitative characteristics of the lumbar multifidi muscles: Comparison of the magnetic resonance imaging and musculoskeletal ultrasound.Interventional pain medicine · 2025Article
- Radiological frontiers in understanding paraspinal muscle pathophysiology in chronic low back pain.Frontiers in medicine · 2025Review
- Association of weight-adjusted waist index and body mass index with chronic low back pain in American adults: a retrospective cohort study and predictive model development based on machine learning algorithms (NHANES 2009-2010).Frontiers in public health · 2025Article
- Efficacy of acupuncture for lumbar disc herniation: changes in paravertebral muscle and fat infiltration - a multicenter retrospective cohort study.Frontiers in endocrinology · 2024Article
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Authors and funding
12 authors.
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Abstract
objectiveIn chronic low back pain (CLBP), the relationship between spinal pathologies and paraspinal muscles fat infiltration remains unclear. This study aims to evaluate the relationship between MRI findings and paraspinal muscles morphology and fat infiltration in CLBP patients by quantitative MRI.
methodsAll the CLBP patients were enrolled from July 2021 to December 2022 in four medical institutions. The cross-sectional area (CSA) and proton density fat fraction (PDFF) of the multifidus (MF) and erector spinae (ES) muscles at the central level of the L4/5 and L5/S1 intervertebral discs were measured. MRI findings included degenerative lumbar spondylolisthesis (DLS), intervertebral disc degeneration (IVDD), facet arthrosis, disc bulge or herniation, and disease duration. The relationship between MRI findings and the paraspinal muscles PDFF and CSA in CLBP patients was analyzed.
resultsA total of 493 CLBP patients were included in the study (198 females, 295 males), with an average age of 45.68 ± 12.91 years. Our research indicates that the number of MRI findings are correlated with the paraspinal muscles PDFF at the L4/5 level, but is not significant. Moreover, the grading of IVDD is the primary factor influencing the paraspinal muscles PDFF at the L4-S1 level (B
conclusionThe degree of paraspinal muscles fat infiltration in CLBP patients is related to the cumulative or synergistic effects of multiple factors, especially at the L4/L5 level. Although age and BMI are important factors affecting the degree of paraspinal muscles PDFF in CLBP patients, their diagnostic efficacy is moderate.
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