ReviewNature reviews. Endocrinology2024
The challenges of assessing adiposity in a clinical setting.
Review in Nature reviews. Endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Precision or Paradox? AI-Driven Adiposity Imaging in Women With Overweight and Obesity: A Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Trial
- Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Independent Associations of Vitamin D Levels with Visceral Fat and Metabolic Age in Adults: A Retrospective Cross-Sectional Study.Metabolites · 2026Article
- Optimal visceral adipose tissue thresholds that minimize risk for osteoporosis and/or diabetes in midlife women.Journal of the Endocrine Society · 2026Article
- The relationship between abdominal obesity indices and the risk of metabolic dysfunction-associated fatty liver disease: a prospective cohort study.Scientific reports · 2026Article
- Better BMI: Novel Digital Anthropometry Equations for Adiposity Assessment in the Chinese Population.Phenomics (Cham, Switzerland) · 2026Article
- Obesity and risk of immune-mediated inflammatory diseases: a real-world propensity score-matched cohort study using electronic health records.Scientific reports · 2026Article
- Association between CVAI-defined body composition phenotypes and prediabetes outcomes in Chinese adults undergoing health check-ups: a cross-sectional study.Frontiers in nutrition · 2026Article
- Central adiposity and sex are associated with the integrative architecture of physiological networks in healthy youth: a cross-sectional study in a cohort of Chinese college students.Frontiers in physiology · 2026Article
- The lancet commission obesity categories, excess adiposity, and BMI discordance in urban Chinese adults: a cross-sectional survey in Beijing.Frontiers in nutrition · 2026Article
- Misclassification Bias in the Waist-To-Hip Ratio: Implications for Obesity-Related Risk of Incident Type 2 Diabetes.International journal of endocrinology · 2026Article
- Recent Advances in Spectroscopy and Imaging Techniques for Nondestructive Detection of Meat Quality and Safety.Food science & nutrition · 2025Review
- 2024 Clinical Practice Guidelines for the Diagnosis and Pharmacologic Treatment of Overweight and Obesity by the Korean Society for the Study of Obesity.Journal of obesity & metabolic syndrome · 2025Review
- Article
- The association between body mass index and neoadjuvant chemotherapy response in patients with breast cancer.Breast cancer research : BCR · 2025Article
- Biomarkers of aging: from molecules and surrogates to physiology and function.Physiological reviews · 2025Review
- Emerging insights into the role of visceral adipose tissue in diabetic kidney disease.Frontiers in nutrition · 2025Review
- Association between weight-adjusted waist index and chronic obstructive pulmonary disease.PloS one · 2025Article
- Relationship between neck circumference and body composition: a cross-sectional study based on a Chinese population.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To tackle the burden of obesity-induced cardiometabolic disease, the scientific community relies on accurate and reproducible adiposity measurements in the clinic. These measurements guide our understanding of underlying biological mechanisms and clinical outcomes of human trials. However, measuring adiposity and adipose tissue distribution in a clinical setting can be challenging, and different measurement methods pose important limitations. BMI is a simple and high-throughput measurement, but it is associated relatively poorly with clinical outcomes when compared with waist-to-hip and sagittal abdominal diameter measurements. Body composition measurements by dual energy X-ray absorptiometry or MRI scans would be ideal due to their high accuracy, but are not high-throughput. Another important consideration is that adiposity measurements vary between men and women, between adults and children, and between people of different ethnic backgrounds. In this Perspective article, we discuss how these critical challenges can affect our interpretation of research data in the field of obesity and the design and implementation of clinical guidelines.
Indexed as
Identifiers
39009863What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.