Evidence map›Paper›PMID 39009836›Full record

ArticleNature neuroscience2024

A nonoscillatory, millisecond-scale embedding of brain state provides insight into behavior.

David F Parks, Aidan M Schneider, Yifan Xu, Samuel J Brunwasser, Samuel Funderburk, Danilo Thurber, Tim Blanche, Eva L Dyer, David Haussler, Keith B Hengen

Abstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

David F Parks *Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
Aidan M Schneider *Department of Biology, Washington University in Saint Louis, St. Louis, MO, USA.
Yifan XuDepartment of Biology, Washington University in Saint Louis, St. Louis, MO, USA.
Samuel J BrunwasserDepartment of Biology, Washington University in Saint Louis, St. Louis, MO, USA.
Samuel FunderburkDepartment of Biology, Washington University in Saint Louis, St. Louis, MO, USA.ORCID http://orcid.org/0000-0001-5146-2035
Danilo ThurberIndependent researcher, Exeter, NH, USA.
Tim BlancheWhite Matter LLC, Seattle, WA, USA.
Eva L DyerDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-6962-524X
David HausslerDepartment of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.ORCID http://orcid.org/0000-0003-1533-4575
Keith B HengenDepartment of Biology, Washington University in Saint Louis, St. Louis, MO, USA. khengen@wustl.edu.ORCID http://orcid.org/0000-0001-5017-4090

Funding

A Comparative Framework for Modeling the Low-Dimensional Geometry of Neural Population StatesR01EB029852 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI DYER, EVA · 2020 to 2020
$1.1M
National Science Foundation (NSF) ACI-1541349National Science Foundation (NSF) CNS-1730158NIBIB NIH HHS R01 EB029852U.S. Department of Health & Human Services | National Institutes of Health (NIH) 1R01NS118442
6 · The paper itself

Abstract

The most robust and reliable signatures of brain states are enriched in rhythms between 0.1 and 20 Hz. Here we address the possibility that the fundamental unit of brain state could be at the scale of milliseconds and micrometers. By analyzing high-resolution neural activity recorded in ten mouse brain regions over 24 h, we reveal that brain states are reliably identifiable (embedded) in fast, nonoscillatory activity. Sleep and wake states could be classified from 10

Indexed as

BrainNeuronsSleepWakefulnessAnimalsBehavior, AnimalElectroencephalographyMaleMiceMice, Inbred C57BL

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.