Evidence map›Paper›PMID 39009709›Full record

Trial reportScientific reports2024

Nilotinib treatment outcomes in autosomal dominant spinocerebellar ataxia over one year.

Woo-Jin Lee, Jangsup Moon, Yoonhyuk Jang, Yong-Woo Shin, Hyoshin Son, Seoyi Shin, Daejong Jeon, Dohyun Han, Soon-Tae Lee, Kyung-Il Park and 3 more

Abstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Woo-Jin LeeDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Jangsup MoonDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Yoonhyuk JangDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Yong-Woo ShinDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Hyoshin SonDepartment of Neurology, Eunpyeong St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.
Seoyi ShinDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Daejong JeonAdvanced Neural Technologies, Seoul, Republic of Korea.
Dohyun HanProteomics Core Facility, Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea.
Soon-Tae LeeDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Kyung-Il ParkDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Keun-Hwa JungDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Sang Kun LeeDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea.
Kon ChuDepartment of Neurology, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehangno, Jongno-gu, Seoul, 03080, Republic of Korea. stemcell.snu@gmail.com.

Funding

SNUH research fund 0420214010Yuhan pharmaceutical 0620225550
6 · The paper itself

Abstract

We evaluated the efficacy and safety of 1-year treatment with nilotinib (Tasigna

Indexed as

PyrimidinesSpinocerebellar AtaxiasAdultFemaleHumansMaleMiddle AgedProteomicsTreatment OutcomenilotinibPyrimidines

Identifiers

PMID39009709
PMCPMC11251258

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.