ArticleScientific reports2024
On the use of the healthy lifestyle index to investigate specific disease outcomes.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Lifestyle scores and their potential to estimate the risk of multiple non-communicable disease-related endpoints: a systematic review.BMC public health · 2025Pooled it
- Lifestyle Adherence and Metabolic Control in Adults with Type 2 Diabetes: Development of a Lifestyle Compliance Index.Diagnostics (Basel, Switzerland) · 2026Article
- Genetic Risk, Healthy Lifestyle, and Risk Stratification for Diverticulitis.Journal of the American College of Surgeons · 2026Article
- Examining relationship between unhealthy lifestyle and life satisfaction among new students at Tehran University of Medical Sciences.PloS one · 2026Article
- Mortality attributable to modifiable lifestyle factors in the Spanish cohort of the European prospective investigation into cancer and nutrition (EPIC) study.BMC public health · 2025Article
- Lifestyle changes and postmenopausal breast cancer risk in women from the European Prospective Investigation into Cancer and Nutrition.Breast cancer research : BCR · 2025Article
- The 6 pillars of lifestyle medicine and headache disability in Brazil: a cross-sectional, population-based study.The journal of headache and pain · 2025Article
- Plant-based dietary patterns and age-specific risk of multimorbidity of cancer and cardiometabolic diseases: a prospective analysis.The lancet. Healthy longevity · 2025Article
- Can serum metabolic signatures inform on the relationship between healthy lifestyle and colon cancer risk?Cancer & metabolism · 2025Article
- Prospective association of a Lifestyle Risk Factor Index with type 2 diabetes in the Multiethnic Cohort.European journal of nutrition · 2025Article
- The 6 Pillars of Lifestyle Medicine and Prevalence of Cardiovascular and Cardiometabolic Diseases in Brazil: A Cross-Sectional, Population-Based Study Involving 88,531 Adults.American journal of lifestyle medicine · 2025Article
- Molecular Mechanisms of Dietary Compounds in Cancer Stem Cells from Solid Tumors: Insights into Colorectal, Breast, and Prostate Cancer.International journal of molecular sciences · 2025Review
- Digital literacy and its effects on older adults' health: exploring mechanisms and outcomes.Frontiers in public health · 2025Article
- Tanzania's NCD Transition: A Comparative Analysis of Healthy Lifestyle Behaviors for Hypertension Prevention Between Rural and Urban Adults.Inquiry : a journal of medical care organization, provision and financingArticle
Corrections and comments
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Authors and funding
33 authors.
Funding
Abstract
The healthy lifestyle index (HLI), defined as the unweighted sum of individual lifestyle components, was used to investigate the combined role of lifestyle factors on health-related outcomes. We introduced weighted outcome-specific versions of the HLI, where individual lifestyle components were weighted according to their associations with disease outcomes. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), we examined the association between the standard and the outcome-specific HLIs and the risk of T2D, CVD, cancer, and all-cause premature mortality. Estimates of the hazard ratios (HRs), the Harrell's C-index and the population attributable fractions (PAFs) were compared. For T2D, the HR for 1-SD increase of the standard and T2D-specific HLI were 0.66 (95% CI: 0.64, 0.67) and 0.43 (0.42, 0.44), respectively, and the C-index were 0.63 (0.62, 0.64) and 0.72 (0.72, 0.73). Similar, yet less pronounced differences in HR and C-index were observed for standard and outcome-specific estimates for cancer, CVD and all-cause mortality. PAF estimates for mortality before age 80 were 57% (55%, 58%) and 33% (32%, 34%) for standard and mortality-specific HLI, respectively. The use of outcome-specific HLI could improve the assessment of the role of lifestyle factors on disease outcomes, thus enhancing the definition of public health recommendations.
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