Evidence map›Paper›PMID 39009368›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2024

Opioid prescribing requirements to minimize unused medications after an emergency department visit for acute pain: a prospective cohort study.

Raoul Daoust, Jean Paquet, Marcel Émond, Massimiliano Iseppon, David Williamson, Justin W Yan, Jeffrey J Perry, Vérilibe Huard, Gilles Lavigne, Jacques Lee and 4 more

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03953534 (Quantity of Opioids for Acute Pain and Limit Unused Medication), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03953534 completednot on this map

Quantity of Opioids for Acute Pain and Limit Unused Medication (OPUM Study)

TypeobservationalSponsorCentre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de MontrealRan2019 to 2023Enrolled2,240ConditionsAcute Pain
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  3. Preventing harms from first prescriptions of opioids.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Raoul DaoustStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta. raoul.daoust@umontreal.ca.
Jean PaquetStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Marcel ÉmondStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Massimiliano IsepponStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
David WilliamsonStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Justin W YanStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Jeffrey J PerryStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Vérilibe HuardStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Gilles LavigneStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Jacques LeeStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Justine LessardStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Eddy LangStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Alexis CournoyerStudy Centre in Emergency Medicine (Daoust, Paquet, Huard, Lessard, Cournoyer), Centre intégré universitaire de santé et de services sociaux (CIUSSS) du Nord-de-l'Île de-Montréal, Sacré-Coeur Hospital; Département de médecine de famille et médecine d'urgence (Daoust, Huard, Lessard, Cournoyer), Faculté de médecine, Université de Montréal, Montréal, Que.; Département de médecine de famille et de médecine d'urgence (Émond), Faculté de Médecine, Université Laval; Département d'urgence du CHU-Québec (Émond), Québec, Que.; Department of Emergency Medicine (Iseppon), Hôpital Maisonneuve-Rosemont; Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal (CIUSSS du Nord-de-l'Île-de-Montréal) (Williamson, Lavigne); Faculté de Pharmacie (Williamson), Université de Montréal, Montréal, Que.; Division of Emergency Medicine (Yan), Department of Medicine, Western University, London Health Sciences Centre, London, Ont.; Department of Emergency Medicine (Perry), University of Ottawa, Ottawa, Ont.; Faculties of Dental Medicine and Medicine (Lavigne), Université de Montréal, Montréal, Que.; Department of Emergency Services and Scientist (Lee), Clinical Epidemiology Unit, Sunnybrook Health Sciences; Schwartz/Reisman Emergency Medicine Institute (Lee), Mount Sinai Hospital, Toronto, Ont.; Department of Emergency Medicine (Lang), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Quantity of Opioids for Acute Pain and Limit Unused Medication (OPUM) group on behalf of the Network of Canadian Emergency Researchers

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnused opioid prescriptions can be a driver of opioid misuse. Our objective was to determine the optimal quantity of opioids to prescribe to patients with acute pain at emergency department discharge, in order to meet their analgesic needs while limiting the amount of unused opioids.

methodsIn a prospective, multicentre cohort study, we included consecutive patients aged 18 years and older with an acute pain condition present for less than 2 weeks who were discharged from emergency department with an opioid prescription. Participants completed a pain medication diary for real-time recording of quantity, doses, and names of all analgesics consumed during a 14-day follow-up period.

resultsWe included 2240 participants, who had a mean age of 51 years; 48% were female. Over 14 days, participants consumed a median of 5 (quartiles, 1-14) morphine 5 mg tablet equivalents, with significant variation across pain conditions (

interpretationTwo-thirds of opioid tablets prescribed at emergency department discharge for acute pain were unused, whereas opioid requirements varied significantly based on the cause of acute pain. Smaller, cause-specific opioid prescriptions could provide adequate pain management while reducing the risk of opioid misuse.

trial registrationClinicalTrials.gov, no. NCT03953534.

Indexed as

Acute PainAnalgesics, OpioidEmergency Service, HospitalAbdominal PainAdultAgedBack PainDrug PrescriptionsEmergency Room VisitsFemaleFractures, BoneHumansMaleMiddle AgedPractice Patterns, Physicians'Prospective StudiesAnalgesics, Opioid

Identifiers

PMID39009368
PMCPMC11268147

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.