ArticleRespiratory physiology & neurobiology2024
Cardiorespiratory failure induced by inhalation of aerosolized fentanyl in anesthetized rats.
Article in Respiratory physiology & neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- Beyond respiratory depression: acute and delayed pulmonary responses following aerosolized fentanyl exposure.Toxicological sciences : an official journal of the Society of Toxicology · 2026Article
- Effects of Intravenous Bolus Injection of Fentanyl on Phrenic Nerve Activity and Its Response to Hypoxia and Hypercapnia.Journal of pharmacy and pharmacology research · 2026Article
- Comparative analysis of anesthetic protocols in spontaneously hypertensive rats with sepsis-induced hemodynamic instability.Frontiers in veterinary science · 2026Article
- Cardiorespiratory failure and sudden death induced by carfentanil exposure: Involvement of central mu1 opioid receptors.Toxicology and applied pharmacology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Intravenous rapid injection of fentanyl causes respiratory depression (severe apneas), leading to sudden death, which constitutes the deadliest drug reaction among overdoses of synthetic opioids. Here we asked whether acute inhalation of overdose fentanyl would also result in similar respiratory failure and death. The anesthetized and spontaneously breathing rats with tracheal cannulation were exposed to aerosolized fentanyl at 100 mg/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.