Evidence map›Paper›PMID 39008557›Full record

ArticleCirculation2024

Childhood Opportunity and Acute Interstage Outcomes: A National Pediatric Cardiology Quality Improvement Collaborative Analysis.

Benjamin Zielonka, Emily M Bucholz, Minmin Lu, Katherine E Bates, Garick D Hill, Nelangi M Pinto, Lynn A Sleeper, David W Brown

Abstract read
In one paragraph

Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin ZielonkaDepartment of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, MA (B.Z., M.L., L.A.S., D.W.B.).ORCID 0000-0003-1052-9736
Emily M BucholzSection of Cardiology, Department of Pediatrics, Children's Hospital Colorado, University of Colorado, Denver (E.M.B.).ORCID 0000-0003-2815-3597
Minmin LuDepartment of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, MA (B.Z., M.L., L.A.S., D.W.B.).
Katherine E BatesDivision of Cardiology, Department of Pediatrics and Communicable Diseases, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor (K.E.B.).ORCID 0000-0002-2844-7520
Garick D HillDepartment of Pediatrics, Cincinnati Children's Hospital Medical Center, OH (G.D.H.).ORCID 0000-0003-0050-7250
Nelangi M PintoDivision of Cardiology, Department of Pediatrics, Seattle Children's Hospital, University of Washington, WA (N.M.P.).
Lynn A Sleeper *Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, MA (B.Z., M.L., L.A.S., D.W.B.).ORCID 0000-0002-8055-768X
David W Brown *Department of Cardiology, Boston Children's Hospital and Department of Pediatrics, Harvard Medical School, MA (B.Z., M.L., L.A.S., D.W.B.).ORCID 0000-0002-8406-5957

Funding

RESEARCH METHODS IN PEDIATRICS HEART DISEASET32HL007572 · NHLBI · CHILDREN'S HOSPITAL BOSTON · PI Sarah D DE FERRANTI, Jane W. Newburger · 1985 to 2026
$13.0M
NHLBI NIH HHS T32 HL007572
6 · The paper itself

Abstract

backgroundThe interstage period after discharge from stage 1 palliation carries high morbidity and mortality. The impact of social determinants of health on interstage outcomes is not well characterized. We assessed the relationship between childhood opportunity and acute interstage outcomes.

methodsInfants discharged home after stage 1 palliation in the National Pediatric Quality Improvement Collaborative Phase II registry (2016-2022) were retrospectively reviewed. Zip code-level Childhood Opportunity Index (COI), a composite metric of 29 indicators across education, health and environment, and socioeconomic domains, was used to classify patients into 5 COI levels. Acute interstage outcomes included death or transplant listing, unplanned readmission, intensive care unit admission, unplanned catheterization, and reoperation. The association between COI level and acute interstage outcomes was assessed using logistic regression with sequential adjustment for potential confounders.

resultsThe analysis cohort included 1837 patients from 69 centers. Birth weight (

conclusionsZip code COI level is associated with differences in preoperative risk factors and stage 1 palliation hospitalization characteristics. Acute interstage outcomes, although common across the spectrum of childhood opportunity, are not associated with COI level in an era of highly prevalent home monitoring programs. The role of home monitoring in mitigating disparities during the interstage period merits further investigation.

Indexed as

Quality ImprovementFemaleHumansInfantInfant, NewbornMalePalliative CarePatient DischargePatient ReadmissionRegistriesRetrospective StudiesSocial Determinants of HealthTreatment OutcomeUnited Stateschildhood opportunityhypoplastic left heart syndromesingle ventriclesocial disparitiessocioeconomic status

Identifiers

PMID39008557
PMCPMC11251506

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.