Evidence map›Paper›PMID 39008364›Full record

ArticleJournal of animal science2024

Carboxyfullerene C60 preserves porcine sperm by enhancing antioxidant capacity and inhibiting apoptosis and harmful bacteria.

Yuqing Li, Haoqi Xiao, Xue Qin, Haize Zhang, Yi Zheng, Rui Cai, Weijun Pang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Perspectives in porcine semen conservation (liquid and frozen).The Journal of reproduction and development · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuqing LiKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Haoqi XiaoKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Xue QinKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Haize ZhangKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Yi ZhengKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.ORCID 0000-0003-0152-2671
Rui CaiKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.
Weijun PangKey Laboratory of Northwest China's Pig Breading and Reproduction, Ministry of Agriculture and Rural Affairs P.R. China, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.ORCID 0000-0003-1740-6536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study used a porcine model to systematically investigate whether carboxyfullerene C60(CF-C60) can be used for sperm preservation. The results indicated that CF-C60 supplementation can preserve porcine sperm quality during storage at 17 °C. This effect was attributable to an improvement in the antioxidant capacity of sperm through a decrease in the reactive oxygen species (ROS) level. Additionally, CF-C60 can maintain mitochondrial function, inhibit sperm apoptosis through the ROS/Cytochrome C (Cyt C)/Caspase 3 signaling pathway, and mediate suppression of bacterial growth through the effects of ROS. Finally, the results of artificial insemination experiments indicated that insemination with CF-C60-treated sperm can increase the total number of offspring born and reduce the number of deformed piglets. Thus, CF-C60 is safe for use as a component of semen diluent for sperm storage.

Indexed as

AntioxidantsApoptosisFullerenesReactive Oxygen SpeciesSemen PreservationSpermatozoaAnimalsInsemination, ArtificialMaleSwineAntioxidantsfullerene C60FullerenesReactive Oxygen Speciesantioxidantsartificial inseminationcarboxyfullerene C60porcinesperm storage

Identifiers

PMID39008364
PMCPMC11345516

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.