Evidence map›Paper›PMID 39008280›Full record

ArticleEmerging microbes & infections2024

Dysfunctional host cellular immune responses are associated with mortality in melioidosis.

Shelton W Wright, Peeraya Ekchariyawat, Sineenart Sengyee, Rungnapa Phunpang, Adul Dulsuk, Natnaree Saiprom, Ekkachai Thiansukhon, Kovit Pattanapanyasat, Sunee Korbsrisate, T Eoin West and 1 more

Abstract read
In one paragraph

Article in Emerging microbes & infections, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shelton W WrightDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Washington, Seattle, WA, USA.ORCID 0000-0002-1457-9821
Peeraya EkchariyawatDepartment of Microbiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand.
Sineenart SengyeeDepartment of Microbiology and Immunology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Rungnapa PhunpangDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Adul DulsukDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Natnaree SaipromDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Ekkachai ThiansukhonDepartment of Medicine, Udon Thani Hospital, Udon Thani, Thailand.
Kovit PattanapanyasatDepartment of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Sunee KorbsrisateDepartment of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
T Eoin WestDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Washington, Seattle, WA, USA.
Narisara ChantratitaDepartment of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

Funding

Pediatric Critical Care Scientist Development ProgramK12HD047349 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI HEATHER T. KEENAN, Kevin M Watt · 2004 to 2026
$17.0M
Anesthesiology & Perioperative Medicine Training GrantT32GM086270 · NIGMS · UNIVERSITY OF WASHINGTON · PI Tonya M Palermo · 2009 to 2026
$4.3M
Integrated Multi-omics of MelioidosisR01AI137111 · NIAID · UNIVERSITY OF WASHINGTON · PI GHARIB, SINA A, WEST, TIMOTHY EOIN · 2018 to 2021
$3.2M
Determinants of Outcome and Recurrent Infections in MelioidosisU01AI115520 · NIAID · MAHIDOL UNIVERSITY · PI CHANTRATITA, NARISARA, WEST, TIMOTHY EOIN · 2015 to 2019
$2.0M
Pulmonary gamma-delta T cells in lung infectionK08HL157562 · NHLBI · UNIVERSITY OF WASHINGTON · PI WRIGHT, SHELTON WILEY · 2021 to 2025
$804k
Multi-omics of murine respiratory melioidosisR21AI178273 · NIAID · UNIVERSITY OF WASHINGTON · PI GHARIB, SINA A, WEST, TIMOTHY EOIN · 2023 to 2024
$428k
NHLBI NIH HHS K08 HL157562NIAID NIH HHS R01 AI137111NIAID NIH HHS R21 AI178273NIAID NIH HHS U01 AI115520NICHD NIH HHS K12 HD047349NIGMS NIH HHS T32 GM086270Wellcome Trust
6 · The paper itself

Abstract

Melioidosis is a tropical infection caused by the intracellular pathogen

Indexed as

Burkholderia pseudomalleiCD8-Positive T-LymphocytesMelioidosisTh17 CellsAdultAgedCD4-Positive T-LymphocytesCytokinesFemaleHumansImmunity, CellularInterleukin-17MaleMiddle AgedProspective StudiesCytokinesInterleukin-17cellular immunityhost immune responseLMICMelioidosissepsis

Identifiers

PMID39008280
PMCPMC11293272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.