Evidence map›Paper›PMID 39008066›Full record

ReviewEuropean journal of nuclear medicine and molecular imaging2024

Preclinical SPECT and PET: Joint EANM and ESMI procedure guideline for implementing an efficient quality control programme.

Christian Vanhove, Michel Koole, Pedro Fragoso Costa, Margret Schottelius, Julia Mannheim, Claudia Kuntner, Geoff Warnock, Wendy McDougald, Adriana Tavares, Monique Bernsen

Erratum issuedAbstract readReview
In one paragraph

Review in European journal of nuclear medicine and molecular imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Pre-clinical SPECT and SPECT-CT in Oncology.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Christian VanhoveDepartment of Electronics and Information Systems, Faculty of Engineering and Architecture, Campus UZ Gent, Institute Biomedical Engineering and Technology (IBiTech), Corneel Heymanslaan 10, 9000, Ghent, Belgium. Christian.Vanhove@UGent.be.ORCID 0000-0002-3988-5980
Michel KooleNuclear Medicine and Molecular Imaging, KU Leuven, Louvain, Belgium.
Pedro Fragoso CostaDepartment of Nuclear Medicine, University Hospital Essen, West German Cancer Center (WTZ), University of Duisburg-Essen, Essen, Germany.
Margret SchotteliusUnit of Translational Radiopharmaceutical Sciences, Departments of Nuclear Medicine and of Oncology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
Julia MannheimDepartment of Preclinical Imaging and Radiopharmacy, Werner Siemens Imaging Center, Eberhard-Karls University Tübingen, Tübingen, Germany.
Claudia KuntnerDepartment of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Geoff WarnockUniversity of Zurich, Zurich, Switzerland.
Wendy McDougaldBHF-University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Adriana TavaresBHF-University Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK.
Monique BernsenAMIE Core Facility, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this guideline is to provide recommendations for the implementation of an effective and efficient quality control (QC) programme for SPECT and PET systems in a preclinical imaging lab. These recommendations aim to strengthen the translational power of preclinical imaging results obtained using preclinical SPECT and PET. As for clinical imaging, reliability, reproducibility, and repeatability are essential when groups of animals are used in a longitudinal imaging experiment. The larger the variability of the imaging endpoint, the more animals are needed to be able to observe statistically significant differences between groups. Therefore, preclinical imaging requires quality control procedures to maintain reliability, reproducibility, and repeatability of imaging procedures, and to ensure the accuracy and precision of SPECT and PET quantification. While the Physics Committee of the European Association of Nuclear Medicine (EANM) has already published excellent procedure guidelines for Routine Quality Control Recommendations for Nuclear Medicine Instrumentation that also includes procedures for small animal PET systems, and important steps have already been made concerning preclinical quality control aspects, this new guideline provides a review and update of these previous guidelines such that guidelines are also adapted to new technological developments.

Indexed as

Positron-Emission TomographyQuality ControlTomography, Emission-Computed, Single-PhotonAnimalsEuropeGuidelines as TopicModels, AnimalNuclear MedicineGuidelinePETPreclinicalQuality controlSPECT

Identifiers

PMID39008066
PMCPMC11527901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.